1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione
5-Ethynyl Uridine
CAS: 69075-42-9;84558-90-7
Molecular Formula: C11H12N2O6
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione - Names and Identifiers
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione - Physico-chemical Properties
| Molecular Formula | C11H12N2O6 |
| Molar Mass | 268 |
| Density | 1.67±0.1 g/cm3(Predicted) |
| Melting Point | >164oC (dec.) |
| Solubility | DMSO (Slightly), Methanol (Very Slightly, Heated, Sonicated) |
| Appearance | Solid |
| Color | Off-White to Pale Beige |
| pKa | 8.29±0.10(Predicted) |
| Storage Condition | -20°C |
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione - Risk and Safety
| HS Code | 29335990 |
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione - Introduction
5-Ethynyl Uridine is an important compound with the following properties:
1. chemical properties: 5-Ethynyl Uridine is a white crystalline solid, can be dissolved in water. It belongs to the nucleoside compound, the structure contains a Ulaimoline base and a ribose. Under acidic conditions, the uraimoline base will exist in the protonated form.
2. use: 5-Ethynyl Uridine has important application value in biological research. It can be used as a synthetic precursor of nucleic acid and participate in experimental techniques such as nucleic acid modification and labeling. In addition, it is used to study the design and development of nucleotide-based drugs.
3. Preparation method: There are many ways to prepare 5-Ethynyl Uridine. One common method is to react uridine with tribromoacetylene to give 5-Ethynyl Uridine.
4. Safety information: 5-Ethynyl Uridine are generally relatively safe under normal conditions of use. However, as a chemical, it still has some safety considerations. For example, inhalation of dust or vapors should be avoided, and contact with skin and eyes should be avoided. Appropriate protective measures should be taken when using, such as wearing gloves and protective glasses. During storage and handling, it should be kept in a sealed container away from fire and oxidizing agents.
1. chemical properties: 5-Ethynyl Uridine is a white crystalline solid, can be dissolved in water. It belongs to the nucleoside compound, the structure contains a Ulaimoline base and a ribose. Under acidic conditions, the uraimoline base will exist in the protonated form.
2. use: 5-Ethynyl Uridine has important application value in biological research. It can be used as a synthetic precursor of nucleic acid and participate in experimental techniques such as nucleic acid modification and labeling. In addition, it is used to study the design and development of nucleotide-based drugs.
3. Preparation method: There are many ways to prepare 5-Ethynyl Uridine. One common method is to react uridine with tribromoacetylene to give 5-Ethynyl Uridine.
4. Safety information: 5-Ethynyl Uridine are generally relatively safe under normal conditions of use. However, as a chemical, it still has some safety considerations. For example, inhalation of dust or vapors should be avoided, and contact with skin and eyes should be avoided. Appropriate protective measures should be taken when using, such as wearing gloves and protective glasses. During storage and handling, it should be kept in a sealed container away from fire and oxidizing agents.
Last Update：2024-04-09 20:45:29
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View History
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione
2-amino-8-methyl-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
Acetcarbromal
1-(3,5-dichlorophenyl)-3-(4-phenyl-1-piperazinyl)-2,5-pyrrolidinedione
1,3-Bis[5-broMo-2-(trifluoroMethyl)phenyl]triaz-1-ene
138772-01-7
BIO-FARMA BF001764
380344-28-5
2-(5-ethyl-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-Dioxaborolane
3-(3-bromophenyl)-6-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
2-amino-8-methyl-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
Acetcarbromal
1-(3,5-dichlorophenyl)-3-(4-phenyl-1-piperazinyl)-2,5-pyrrolidinedione
1,3-Bis[5-broMo-2-(trifluoroMethyl)phenyl]triaz-1-ene
138772-01-7
BIO-FARMA BF001764
380344-28-5
2-(5-ethyl-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-Dioxaborolane
3-(3-bromophenyl)-6-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole