Molecular Formula | C25H38O3 |
Molar Mass | 386.57 |
Density | 1.030±0.06 g/cm3(Predicted) |
Melting Point | 141-142° |
Boling Point | 470.1±45.0 °C(Predicted) |
Specific Rotation(α) | D +227° (CHCl3) |
Solubility | DMSO: soluble |
Appearance | solid |
pKa | 9.72±0.60(Predicted) |
Storage Condition | −20°C |
WGK Germany | 3 |
biological activity | Dexanabinol (HU-211) is a synthetic cannabinoid derivative that lacks cannabinoid effects. Dexanabinol not only shows antioxidant and neuroprotective effects in the brain, but also has anti-inflammatory activity of inhibiting NF-κB and reducing cytokines such as TNFα and interleukin-6 (IL-6), which can ensure the integrity of the BBB, reduced apoptosis and death. Dexanabinol is widely used in head injury or stroke studies and has been shown to be safe in animals and humans. |