(aR,3aS,4S,6S,7aR)-alpha-Ethylhexahydro-3a,5,5-trimethyl-4,6... - Names and Identifiers
Name | (aR,3aS,4S,6S,7aR)-alpha-Ethylhexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborole-2-methanamine trifluoroacetate
|
Synonyms | (r)-boroabu-(+)-pinanediol-cf3co2h (R)-BoroAbu-(+)-Pinanediol-CF3CO2H (aR,3aS,4S,6S,7aR)-alpha-Ethylhexahydro-3a,5,5-trimethyl-4,6... (aR,3aS,4S,6S,7aR)-alpha-Ethylhexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborole-2-methanamine trifluoroacetate
|
CAS | 208521-43-1
|
(aR,3aS,4S,6S,7aR)-alpha-Ethylhexahydro-3a,5,5-trimethyl-4,6... - Physico-chemical Properties
(aR,3aS,4S,6S,7aR)-alpha-Ethylhexahydro-3a,5,5-trimethyl-4,6... - Introduction
(aR,3aS,4S,6S,7aR)-alpha-Ethylhexahydro-3a,5,5-trimethyl-4,6-methano-1,3, trifluoroacetate, abbreviated as (R,R,R)-BOROX-M, it is an organic boron compound. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
(R,R,R)-BOROX-M is a colorless or slightly yellow solid, soluble in some organic solvents, such as methylene chloride, ether and acetone. It is a chiral compound with potential applications in asymmetric catalytic reactions. The crystal structure of this compound has a ring structure of trioxaborane in which a boron atom forms a bond with three oxygen atoms. The chiral structure of this compound allows it to exhibit good selectivity in chiral catalytic reactions.
Use:
(R,R,R)-BOROX-M, as a chiral catalyst, has a wide range of applications in the synthesis of organic compounds and the preparation of drugs. It can participate in asymmetric addition reactions, cyclization reactions and cross-coupling reactions of various carbonyl compounds. In addition, it can also be applied to the construction and functionalization of chiral nitrogen heterocyclic compounds in organic synthesis.
Method:
The synthesis of (R,R,R)-BOROX-M usually uses certain Chiral reagents for asymmetric transamidation to obtain chiral BOROX-M intermediates. Then, (R,R,R) is formed by adding a mixture of boron trioxide and methylamine-BOROX-M the specific synthesis method may vary according to different research needs.
Safety Information:
(R,R,R)-BOROX-M compounds that are considered relatively safe under general conditions of use. However, as with all chemicals, care should be taken for safe handling. Care should be taken to avoid contact with skin and eyes, and should be operated in a well-ventilated area. If swallowed or inhaled, seek medical help immediately.
Last Update:2024-04-09 20:52:54