(S)-3-Hydroxypiperidine - Names and Identifiers
(S)-3-Hydroxypiperidine - Physico-chemical Properties
Molecular Formula | C5H11NO
|
Molar Mass | 101.15 |
Density | 1.016±0.06 g/cm3(Predicted) |
Boling Point | 191.9±23.0 °C(Predicted) |
pKa | 14.91±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
(S)-3-Hydroxypiperidine - Introduction
(S)-3-Hydroxypiperidine is an organic compound with the chemical formula C5H11NO, which structurally contains a piperidine ring and a hydroxyl functional group.
Nature:
(S)-3-Hydroxypiperidine is a colorless or white crystalline solid, soluble in ethanol and ether, and slightly soluble in water. It has a density of 1.003g/cm3 and a boiling point of 215-217 ° C. The optical rotation of this compound was [α]D = 5 ° to 9 ° (chloroform).
Use:
(S)-3-Hydroxypiperidine is an important raw material for the synthesis of drugs and intermediates. It can be used to synthesize a variety of drugs, including antidepressants, analgesics, antineoplastic drugs, etc.
Method:
(S)-3-Hydroxypiperidine can be prepared by a variety of methods. A common method is to obtain the target product by reacting piperidine with sodium hydroxide (NaOH) in an alcohol solvent, followed by acidification.
Safety Information:
(S)-3-Hydroxypiperidine has low toxicity, but as an organic compound, attention should be paid to correct storage and operation. Avoid contact with skin, eyes and respiratory tract. Wear appropriate protective equipment such as lab gloves, glasses, and protective masks when using. If exposed or inhaled, rinse immediately with plenty of water or seek medical attention. When stored, it should be placed in a dry, clean, well-ventilated place, away from fire and oxidizing agents.
Last Update:2024-04-09 19:05:48