(S)-3-Hydroxy-gamma-butyrolactone

(S)-3-Hydroxy-gamma-butyrolactone - Names and Identifiers

Name	(S)-3-hydroxy-gamma-butyrolactone
Synonyms	(S)-3-HYDROXYBUTYROLACTONE (S)-3-Hydroxybutyrolactone S-3-HYDROXY-γ-BUTYROLACTONE 3-hydroxy gamma butyrolactone (S)-(-)-3-HYDROXYBUTYROLACTONE S-(-)-3-hydroxy-γ-butyrolactone 4-hydroxydihydrofuran-2(3H)-one (S)-(-)-3-Hydroxy-γ-butyrolactone (S)-3-hydroxy-gamma-butyrolactone (S)-(-)-3-Hydroxy-T-butyrolactone (S)-4-HYDROXYTETRAHYDROFURAN-2-ONE (4S)-4-hydroxydihydrofuran-2(3H)-one (S)-(-)-3-HYDROXY-GAMA-BUTYROLACTONE (5S)-5-hydroxydihydrofuran-2(3H)-one (S)-(-)-3-HYDROXY-GAMMA-BUTYROLACTONE S-(-)-beta-Hydroxy-gamma-Butyrolactone 2(3H)-FURANONE, DIHYDRO-4-HYDROXY-, (S) 2(3H)-FURANONE, DIHYDRO-3-HYDROXY-, (S) (S)-4,5-DIHYDRO-4-HYDROXY-2(3H)-FURANONE
CAS	7331-52-4 5469-16-9
EINECS	434-990-4
InChI	InChI=1/C4H6O3/c5-3-1-4(6)7-2-3/h3,5H,1-2H2/t3-/m0/s1

(S)-3-Hydroxy-gamma-butyrolactone - Physico-chemical Properties

Molecular Formula	C4H6O3
Molar Mass	102.09
Density	1.241g/mLat 25°C(lit.)
Melting Point	1.24
Boling Point	98-100°C0.3mm Hg(lit.)
Flash Point	>230°F
Water Solubility	Miscible with water, alcohol and other organic solvent. Immiscible with light petroleum.
Vapor Presure	5.42E-05mmHg at 25°C
BRN	1280864
pKa	12.87±0.20(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	n20/D 1.464(lit.)
Physical and Chemical Properties	(s)-3-hydroxy-gamma butyrolactone is a colorless liquid, soluble in water, alcohol and other organic solvents, insoluble in petroleum ether, etc., it is a very important organic synthesis intermediates, it is also a very important source of chirality. Mainly used as a key intermediate of Modulator (R)-gamma-hydroxy-beta-Q hydroxybutyric acid [(R)-GABOB],(R)-GABOB is used to treat hyperlipidemia;(s)-Oxiracetam is a promoter of brain metabolism, but also its synthesis; Its reduction can be obtained (s)-3-hydroxytetrahydrofuran, which is an important intermediate for the treatment of AIDS drugs; the (s)-3-hydroxy-4-bromobutyric acid synthesized from it is a potential stabilizer; It is converted into (s)-5-hydroxymethyl-1, 3-oxazolin-2-one available for the latest generation of antibacterial drugs; In addition,(s)-n-methyl-3-hydroxypyrrole and (R)--N-methyl -3-methyl-pyrrole also has important physiological activity, can also be obtained by simple conversion of (s)-3-hydroxy-gamma butyrolactone. Many natural products can also be synthesized from (s)-3-hydroxy-γbutyrolactone.

(S)-3-Hydroxy-gamma-butyrolactone - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
FLUKA BRAND F CODES	3-10
HS Code	29322090

(S)-3-Hydroxy-gamma-butyrolactone - Reference Information

purpose

used as intermediate in organic synthesis
atorvastatin calcium intermediate
It is a very important intermediate in organic synthesis, it is also a very important source of chirality. Mainly used as a key intermediate of Modulator (R)-gamma-hydroxy-beta-Q hydroxybutyric acid [(R)-GABOB],(R)-GABOB is used to treat hyperlipidemia;(s)-Oxiracetam is a promoter of brain metabolism, but also its synthesis; Its reduction can be obtained (s)-3-hydroxytetrahydrofuran, which is an important intermediate for the treatment of AIDS drugs; the (s)-3-hydroxy-4-bromobutyric acid synthesized from it is a potential stabilizer; It is converted into (s)-5-hydroxymethyl-1, 3-oxazolin-2-one available for the latest generation of antibacterial drugs; In addition,(s)-n-methyl-3-hydroxypyrrole and (R)--

Last Update：2024-04-09 21:11:58

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View History

(S)-3-Hydroxy-gamma-butyrolactone
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(S)-3-Hydroxy-gamma-butyrolactone

(S)-3-hydroxy-gamma-butyrolactone

CAS: 7331-52-4;5469-16-9

Molecular Formula: C4H6O3

(S)-3-Hydroxy-gamma-butyrolactone - Names and Identifiers

(S)-3-Hydroxy-gamma-butyrolactone - Physico-chemical Properties

(S)-3-Hydroxy-gamma-butyrolactone - Risk and Safety

(S)-3-Hydroxy-gamma-butyrolactone - Reference Information

Supplier List

(S)-3-Hydroxy-gamma-butyrolactone Request for Quotation

(S)-3-hydroxy-gamma-butyrolactone

CAS: 7331-52-4;5469-16-9

Molecular Formula: C4H6O3

(S)-3-Hydroxy-gamma-butyrolactone - Names and Identifiers

(S)-3-Hydroxy-gamma-butyrolactone - Physico-chemical Properties

(S)-3-Hydroxy-gamma-butyrolactone - Risk and Safety

(S)-3-Hydroxy-gamma-butyrolactone - Reference Information

Supplier List

(S)-3-Hydroxy-gamma-butyrolactone