(S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
(S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid is a solid with a white to pale yellow color. Its chemical formula is C10H10F3NO2 and its molecular weight is 227.18. It is a chiral molecule with an (S) stereoisomer.
Use:
This compound has a wide range of applications in the field of chemistry and pharmacy. It can be used as a pharmaceutical intermediate for the synthesis of drugs, such as chloroquine, hydroxychloroquine, pembrolizumab, etc. It can also be used as catalysts and reagents in organic synthesis reactions.
Preparation Method:
(S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid is usually prepared by chemical synthesis. Specific preparation methods include:
1. First synthesize (S)-3-amino -3-(4-trifluoromethylphenyl) propanol, and then convert it to the corresponding acid form.
2. The target compound is synthesized from an appropriate chiral precursor by using a chiral synthesis method.
Safety Information:
Limited safety information regarding (S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid. Therefore, when using or handling the compound, it is necessary to comply with the relevant safety procedures. This includes wearing appropriate protective equipment, avoiding contact with skin and eyes, and ensuring that you operate in a well-ventilated environment. If necessary, it should be used under the guidance of chemical professionals.