(S)-3-(4-氟苯基)-B-氨基丙醇

(S)-3-(4-氟苯基)-B-氨基丙醇 - Names and Identifiers

Name	(3S)-3-Amino-3-(4-fluorophenyl)propan-1-ol
Synonyms	(S)-3-(4-Fluorophenyl)-β-alaninol (S)-3-(4-FLUOROPHENYL)-BETA-ALANINOL (S)-3-(4-fluorophenyl)-beta-alaninol HCl (3S)-3-Amino-3-(4-fluorophenyl)propan-1-ol (3S)-3-amino-3-(4-fluorophenyl)propan-1-ol (S)-beta-(4-Fluorophenyl)alaninol hydrochloride benzenepropanol, gamma-amino-4-fluoro-, (gammaS)- Benzenepropanol, .gamma.-amino-4-fluoro-, (.gamma.S)-
CAS	228422-49-9
InChI	InChI=1/C9H12FNO/c10-8-3-1-7(2-4-8)9(11)5-6-12/h1-4,9,12H,5-6,11H2/t9-/m0/s1

(S)-3-(4-氟苯基)-B-氨基丙醇 - Physico-chemical Properties

Molecular Formula	C9H12FNO
Molar Mass	169.2
Density	1.168g/cm³
Boling Point	296.827°C at 760 mmHg
Flash Point	133.316°C
Vapor Presure	0.001mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.541

(S)-3-(4-氟苯基)-B-氨基丙醇 - Introduction

(3S)-3-Amino-3-(4-fluorophenyl)propan-1-ol, also known as (3S)-3-Amino-3-(4-fluorophenyl)propan-1-ol, is a chemical substance. Its molecular formula is C9H12FNO and its molecular weight is 167.20.

Nature:
-Appearance: A colorless or white crystal or crystalline powder
-Melting Point: 71-73 ℃
-Boiling point: 315.7 ℃ (predicted value)
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and methanol

Use:
(3S)-3-Amino-3-(4-fluorophenyl)propan-1-ol is widely used in the field of medicine, mainly for the synthesis of drugs or drug intermediates. It can be used as a chiral ligand to participate in asymmetric catalytic reactions in organic synthesis to produce biologically active compounds. In addition, it can be used to synthesize potential anticancer drugs and other drugs.

Method:
A common preparation method is to reduce 4-fluoroacetophenone to obtain (3S)-3-Amino-3-(4-fluorophenyl)propan-1-ol. Specific reaction conditions and steps can be adjusted and optimized according to actual needs.

Safety Information:
The specific toxicity of the (3S)-3-Amino-3-(4-fluorophenyl)propan-1-ol has not been fully evaluated and therefore requires general laboratory safety measures. During handling and use, appropriate personal protective measures should be observed, such as wearing gloves, goggles and laboratory coats. It also requires effective ventilation and avoids contact with skin and eyes. In case of any accident, flush the affected area with water immediately and seek medical assistance.

Last Update：2024-04-09 20:49:11