(S)-2-Hydroxy-gamma-butyrolactone

(S)-2-Hydroxy-gamma-butyrolactone - Names and Identifiers

Name	(S)-(-)-alpha-hydroxy-gamma-butyrolactone
Synonyms	(S)-2-Hydroxy-gamma-butyrolactone (3S)-3-hydroxytetrahydrofuran-2-one S-(-)-3-Hydroxy-gamma-butyrolactone (S)-3-hydroxydihydrofuran-2(3H)-one (S)-(-)-ALPHA-HYDROXY--BUTYROLACTONE (3S)-3-HYDROXYDIHYDROFURAN-2(3H)-ONE (3S)-3-hydroxydihydrofuran-2(3H)-one (3S)-Dihydro-3-hydroxy-2(3H)-furanone (S)-(-)-alpha-Hydroxy-gamma-butyrolactone (S)-(-)-alpha-hydroxy-gamma-butyrolactone 2,4-Dihydroxybutyric acid lactone(S)-2-Hydroxybutyrolactone
CAS	52079-23-9
EINECS	434-990-4
InChI	InChI=1/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2/t3-/m0/s1

(S)-2-Hydroxy-gamma-butyrolactone - Physico-chemical Properties

Molecular Formula	C4H6O3
Molar Mass	102.09
Density	1.309g/mLat 25°C(lit.)
Boling Point	133°C10mm Hg(lit.)
Specific Rotation(α)	-68 º (c=1.15 in chloroform)
Flash Point	>230°F
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	0.00371mmHg at 25°C
Appearance	Oil
Specific Gravity	1.3
Color	Colourless to Light Yellow
pKa	13.07±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	n20/D 1.467(lit.)

(S)-2-Hydroxy-gamma-butyrolactone - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29322090

(S)-2-Hydroxy-gamma-butyrolactone - Introduction

(S)-(-)-alpha-hydroxy-gamma-butyrolactone is an organic compound with the chemical formula C4H6O3. It is a colorless liquid, at room temperature can be dissolved in a variety of organic solvents.

For the use of (S)-(-)-alpha-hydroxy-gamma-butyrolactone, it is widely used in organic synthesis. It is an important chiral intermediate, which can be used in the synthesis of bioactive compounds, drugs and pesticides. It can also function as a catalyst and solvent in certain chemical reactions.

The (S)-(-)-alpha-hydroxy-gamma-butyrolactone can be synthesized by asymmetric synthesis or enantioselective chemical conversion. Among them, the common method is to modify the existing chiral compounds or to achieve by asymmetric catalytic reaction.

In terms of safety information,(S)-(-)-alpha-hydroxy-gamma-butyrolactone are generally low-toxic compounds. However, depending on the nature and use of the chemical, it may be irritating to the human body and needs to be handled in accordance with safe operating procedures. When using, pay attention to avoid direct contact with skin and eyes, and maintain good ventilation conditions.

Last Update：2024-04-09 21:54:55