(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline - Names and Identifiers
Name | (S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline
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Synonyms | Dextromethorphan Impurity 16 Dextromethorphan Impurity 12 1-(4-METHOXY-BENZYL)-1,2,3,4,5,6,7,8-OCTAHYDRO-ISOQUINOLINE (S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline (S)-1,2,3,4,5,6,7,8-octahydro-1-[(4-methoxyphenyl)methyl]isoquinoline Isoquinoline,1,2,3,4,5,6,7,8-octahydro-1-[(4-Methoxyphenyl)Methyl]-, (1S)-
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CAS | 30356-07-1
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EINECS | 250-144-5 |
(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline - Physico-chemical Properties
Molecular Formula | C17H23NO
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Molar Mass | 257.37062 |
Density | 1.07±0.1 g/cm3(Predicted) |
Boling Point | 394.8±27.0 °C(Predicted) |
pKa | 10.20±0.40(Predicted) |
Storage Condition | Room Temprature |
(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline - Introduction
(S)-1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, also known as (S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(S)-1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline has the molecular formula C16H21NO, the molecular weight was 247.34g/mol. It is a solid that usually appears as a white to white crystal or powder. The compound is stable at room temperature. It has moderate solubility and can be dissolved in most organic solvents such as methanol, ethanol, dimethylformamide, etc.
Use:
(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7, 8-Octahydroisoquinoline is an important intermediate in organic synthesis. It can be used to synthesize various drug molecules, such as anti-tumor drugs, antidepressants and antihypertensive drugs. In addition, it can also be used to synthesize organic compounds such as pesticides and dyes.
Method:
(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7, there are various methods for the preparation of 8-octahydroisoquinoline, but one commonly used method is by reduction and amidation. The specific steps are to chelate the corresponding aromatic ketone with nickel (II) to form a controlled antadine (1,3-BIS diethyl quaternary carbon compound) for paint inspection. In the presence of hydrogen reduction to generate alcohol, and then the alcohol with the appropriate acid chloride reaction, the final amidation reaction can be obtained by the target product.
Safety Information:
(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7, there is limited safety information on 8-octahydroisoquinoline. As a chemical substance, it has a certain potential danger. During operation and use, it is necessary to follow appropriate laboratory safety procedures and use personal protective equipment, such as laboratory gloves and glasses, correctly. In addition, the compound should be kept away from sources of ignition and stored in a well-ventilated area. Persons without professional training should not come into contact with and handle this compound. In the event of an accident, immediately take appropriate first aid measures and seek medical help.
Last Update:2024-04-09 20:52:54