(S)-(-)-4-溴-3-羟丁酸乙酯

(S)-(-)-4-溴-3-羟丁酸乙酯 - Names and Identifiers

Name	Ethyl (S)-4-bromo-3-hydroxybutyrate
Synonyms	Ethyl (S)-4-bromo-3-hydroxybutyrate ETHYL (S)-4-BROMO-3-HYDROXYBUTANOATE ETHYL (3S)-4-BROMO-3-HYDROXYBUTANOATE Ethyl (3S)-4-bromo-3-hydroxybutanoate ETHYL S-(+)-4-BROMO-3-HYDROXYBUTANOATE ETHYL (S)-(-)-4-BROMO-3-HYDROXYBUTYRATE ETHYL-[(3S)-(-)-4-BROM-3-HYDROXYBUTANOAT] (S)-4-BROMO-3-HYDROXYBUTANOATE ETHYL ESTER (S)-4-BROMO-3-HYDROXYBUTYRIC ACID ETHYL ETHER BUTANOIC ACID 4-BROMO-3-HYDROXY-ETHYL ESTER, (S) BUTANOIC ACID, 4-BROMO-3-HDROXY-, ETHYL ESTER, (S) butanoic acid, 4-bromo-3-hydroxy-, ethyl ester, (3S)-
CAS	95537-36-3
InChI	InChI=1/C6H11BrO3/c1-2-10-6(9)3-5(8)4-7/h5,8H,2-4H2,1H3/t5-/m0/s1

(S)-(-)-4-溴-3-羟丁酸乙酯 - Physico-chemical Properties

Molecular Formula	C6H11BrO3
Molar Mass	211.05
Density	1.468g/mLat 25°C(lit.)
Melting Point	94-96℃ (p=2torr)
Boling Point	94-96°C2mm Hg(lit.)
Flash Point	>230°F
Vapor Presure	0.000329mmHg at 25°C
Appearance	Liquid
Specific Gravity	1.468
Color	Colorless to Brown
pKa	13.03±0.20(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	n20/D 1.474(lit.)

(S)-(-)-4-溴-3-羟丁酸乙酯 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	41 - Risk of serious damage to eyes
Safety Description	S39 - Wear eye / face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3

(S)-(-)-4-溴-3-羟丁酸乙酯 - Introduction

Ethyl (S)-is an organic compound with a chemical formula of C6H11BrO3 and a molecular weight of 211.05g/mol. It is a chiral compound prepared by the reaction of (S)-3-hydroxybutyric acid and bromoethanol.

Ethyl (S)-is a colorless liquid with a distinct fragrance at room temperature. It is soluble in organic solvents such as ether and acetone and insoluble in water. It has a melting point of -35°C and a boiling point of 245-246°C.

It is often used as a chiral reagent in organic synthesis for the synthesis of physiologically active chiral compounds. It can be used as a reagent or intermediate for the preparation of compounds such as drugs, pesticides and medical chemicals.

The method for preparing Ethyl (S)-is generally to react (S)-3-hydroxybutyric acid with bromoethanol under alkaline conditions. Usually, the hydroxyl group of (S)-3-hydroxybutyric acid can be protected as a hydroxyl ether in the presence of a basic catalyst, and then bromination reaction can be carried out to form the desired product.

General laboratory practices should be followed for safety information. The compound should be handled in a well-ventilated area, avoiding inhalation, contact with skin and eyes. Wear protective glasses and gloves if necessary. In case of inhalation or contact, seek medical attention immediately. Storage should be sealed, away from fire and oxidant.

Last Update：2024-04-09 20:02:46