(R)-2-氨基-3-(3,5-二氟苯基)丙酸 - Names and Identifiers
Name | 3,5-Difluoro-D-phenylalanine
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Synonyms | uoro-D-phenyL D-Phe(3,5-DiF)-OH D-3,5-Difluoro-phe-OH 5-difluorophenyl)-D-alanine D-3,5-Difluorophenylalanine 3,5-Difluoro-D-phenylalanine D-Phenylalanine,3,5-difluoro- 3-(3,5-DIFLUOROPHENYL)-D-ALANINE (R)-2-aMino-3-(3,5-difluorophenyl)propanoic acid
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CAS | 266360-63-8
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InChI | InChI=1/C9H9F2NO2/c10-6-1-5(2-7(11)4-6)3-8(12)9(13)14/h1-2,4,8H,3,12H2,(H,13,14)/t8-/m1/s1 |
(R)-2-氨基-3-(3,5-二氟苯基)丙酸 - Physico-chemical Properties
Molecular Formula | C9H9F2NO2
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Molar Mass | 201.17 |
Density | 1.379g/cm3 |
Boling Point | 295.1°C at 760 mmHg |
Flash Point | 132.3°C |
Vapor Presure | 0.000704mmHg at 25°C |
Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
Refractive Index | 1.536 |
MDL | MFCD01631988 |
(R)-2-氨基-3-(3,5-二氟苯基)丙酸 - Introduction
3,5-difluoro-D-phenylalanine, also known as 3,5-difluoro-D-phenylalanine, is an organic compound. Its chemical formula is C9H10F2NO2 and its molecular weight is 201.18. This compound is a derivative of D-phenylalanine having two fluorine atoms substituted for carbon atoms 3 and 5 of the phenyl ring.
3,5-difluoro-D-phenylalanine has the appearance of a white crystalline solid. It has a melting point of about 250-252 ° C. The compound is stable at room temperature and is less sensitive to moisture and light.
In the field of medicinal chemistry, 3,5-difluoro-D-phenylalanine can be used as one of the raw materials for the synthesis of drugs. Its substitution of two fluorine atoms on the benzene ring can change the physicochemical properties and pharmaceutical activity of the compound, which has potential drug development applications.
To prepare 3,5-difluororo-D-phenylalanine, a common method is to fluorinate D-phenylalanine. The fluorination reaction can be carried out by various methods, such as direct fluorination of a fluorinating agent, oxyfluorination chlorofluorination production reaction, and regioselective fluorination reaction by a fluorinating agent.
Regarding safety information, under normal operating conditions, 3,5-difluoro-D-phenylalanine has a low risk. However, when operating, it is still necessary to pay attention to protective measures, such as wearing protective gloves and goggles to ensure adequate ventilation. Avoid contact with flammable substances during storage and handling, and store them in a dry, well-ventilated place.
Last Update:2024-04-09 20:02:46