(R)-1-Boc-3-羧基吡咯烷
(R)-1-Boc-pyrrolidine-3-carboxylic acid
CAS: 72925-16-7
Molecular Formula: C10H17NO4
(R)-1-Boc-3-羧基吡咯烷 - Names and Identifiers
| Name | (R)-1-Boc-pyrrolidine-3-carboxylic acid |
| Synonyms | BOC-L-B-PROLINE (3S)-BOC-BETA-PRO-OH (S)-1-N-BOC-BETA-PROLINE (R)-1-N-Boc-beta-proline S-1-BOC-PYRROLIDINE-3-CARBOXYLIC ACID (R)-n-Boc-pyrrolidine-3-carboxylic acid (R)-1-Boc-pyrrolidine-3-carboxylic acid (3S)-BOC-1-PYRROLIDINE-3-CARBOXYLIC ACID BOC-(3S)-1-PYRROLIDINE-3-CARBOXYLIC ACID (R)-1-tert-Butoxycarbonyl-pyrrolidine-3-carboxylic acid (3R)-1-(tertbutoxycarbonyl)pyrrolidine-3-carboxylic acid (S)-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER |
| CAS | 72925-16-7 |
| EINECS | 674-617-4 |
| InChI | InChI=1/C10H17NO4/c1-10(2,3)15-9(14)11-5-4-7(6-11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m1/s1 |
(R)-1-Boc-3-羧基吡咯烷 - Physico-chemical Properties
| Molecular Formula | C10H17NO4 |
| Molar Mass | 215.25 |
| Density | 1.201±0.06 g/cm3(Predicted) |
| Melting Point | 138-143°C |
| Boling Point | 337.2±35.0 °C(Predicted) |
| Flash Point | 157.7°C |
| Solubility | Soluble in Dimethyl sulfoxide (DMSO). |
| Vapor Presure | 2E-05mmHg at 25°C |
| pKa | 4.47±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.502 |
| MDL | MFCD03094727 |
(R)-1-Boc-3-羧基吡咯烷 - Risk and Safety
| Hazard Symbols | N - Dangerous for the environment |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| HS Code | 29339900 |
(R)-1-Boc-3-羧基吡咯烷 - Introduction
(R)-(R)-(acid) is an organic compound with the following properties:
1. Appearance:(R)-acid is a colorless solid.
2. Chemical properties: It is a pyrrolidine derivative with carboxyl group and protecting group (Boc,tert-butoxycarbonyl). It is stable at room temperature and can be dissolved in some polar solvents, such as dimethyl sulfoxide and dichloromethane.
3. uses:(R)-acid is commonly used in asymmetric synthesis reactions in organic synthesis. It can be used as a building block for chiral backbones for the synthesis of drugs, natural products and other biologically active compounds.
4. preparation method: a common preparation method is through 1-pyrrolidine methanol (pyrrolidine-1-carboxylic acid) and N-tert-butoxycarbonyl-L-alanine (N-tert-Boc-L-alloisoleucine acid) esterification reaction, and through acid hydrolysis to obtain the target product.
5. Safety information:(R)-acid is generally safe under normal use conditions, but as a chemical substance, it may cause harm to human health and the environment. Therefore, during handling and storage, safe operating procedures should be followed and contact with skin, eyes and mucous membranes should be avoided.
1. Appearance:(R)-acid is a colorless solid.
2. Chemical properties: It is a pyrrolidine derivative with carboxyl group and protecting group (Boc,tert-butoxycarbonyl). It is stable at room temperature and can be dissolved in some polar solvents, such as dimethyl sulfoxide and dichloromethane.
3. uses:(R)-acid is commonly used in asymmetric synthesis reactions in organic synthesis. It can be used as a building block for chiral backbones for the synthesis of drugs, natural products and other biologically active compounds.
4. preparation method: a common preparation method is through 1-pyrrolidine methanol (pyrrolidine-1-carboxylic acid) and N-tert-butoxycarbonyl-L-alanine (N-tert-Boc-L-alloisoleucine acid) esterification reaction, and through acid hydrolysis to obtain the target product.
5. Safety information:(R)-acid is generally safe under normal use conditions, but as a chemical substance, it may cause harm to human health and the environment. Therefore, during handling and storage, safe operating procedures should be followed and contact with skin, eyes and mucous membranes should be avoided.
Last Update：2024-04-09 20:48:19
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View History
(R)-1-Boc-3-羧基吡咯烷
1-Butyl-2,3-methylimidazolium Bromide
猪毛蒿-3-O-半乳糖苷(RG)
DISODIUM 2-NAPHTHOL-3,6-DISULFONATE
S-(-)-2-HYDROXY-6-METHOXY-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]BENZAMIDE
N-甲基--4-硝基邻甲苯胺
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[3-(trifluoromethoxy)phenyl]propanoic acid
CR 1936
2-(HYDRAZINYLMETHYL)PYRAZINE HCL
Bis[(perfluorooct-1-yl)sulphonyl]amine
1-Butyl-2,3-methylimidazolium Bromide
猪毛蒿-3-O-半乳糖苷(RG)
DISODIUM 2-NAPHTHOL-3,6-DISULFONATE
S-(-)-2-HYDROXY-6-METHOXY-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]BENZAMIDE
N-甲基--4-硝基邻甲苯胺
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[3-(trifluoromethoxy)phenyl]propanoic acid
CR 1936
2-(HYDRAZINYLMETHYL)PYRAZINE HCL
Bis[(perfluorooct-1-yl)sulphonyl]amine