(Pyrroglutamic Acid)
5-Oxo-DL-proline-d5
CAS: 352431-30-2
Molecular Formula: C5H7NO3
(Pyrroglutamic Acid) - Names and Identifiers
(Pyrroglutamic Acid) - Physico-chemical Properties
| Molecular Formula | C5H7NO3 |
| Molar Mass | 129.12 |
| Melting Point | 175 - 177°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | Refrigerator |
(Pyrroglutamic Acid) - Introduction
5-Oxo-DL-proline-d5 (5-Oxo-DL-proline-d5) is a labeled compound with the following properties:
-molecular formula: C5H3D5NO3
-relative molecular mass: 129.17g/mol
-Appearance: White crystal or crystalline powder
-Melting point: 163-166 ° C
-Soluble: Soluble in water and ethanol
5-Oxo-DL-proline-d5 is commonly used as a labeling reagent in nuclear magnetic resonance (NMR) research to label and track the reaction and metabolism of compounds in biological systems. Due to its stable isotope labeling (embedding of heavy Hydrin D) and clear response in NMR spectrum, 5-Oxo-DL-proline-d5 is widely used in drug research and development, biochemistry, metabolomics and other fields.
The preparation method of 5-Oxo-DL-proline-d5 can be synthesized from natural products or synthetic compounds. A common preparation method is as follows:
1. First, select an appropriate starting compound, such as L-glutamic acid (L-Glutamic acid).
2. In a suitable solvent, the starting compound and heavy water reagent reaction. Common heavy hydrating reagents include heavy water or sodium deuterium oxide (D2O/NaOD).
3. Adjust the reaction conditions, such as temperature and reaction time, to convert the compound into 5-oxo-d1-proline-d5.
4. Finally, the target product is purified and harvested through the steps of crystallization, washing and drying.
In terms of safety, 5-Oxo-DL-proline-d5 has not been reported to be toxic or fatal. However, as an organic compound, normal laboratory safety practices should generally be followed, including wearing appropriate personal protective equipment (such as gloves, goggles, etc.) to avoid contact with skin and eyes, avoid inhalation or ingestion. In case of accidental splashing or contact, rinse immediately with plenty of water. In case of doubt or emergency, seek medical help immediately, consult the relevant agencies and follow the safe operation guidelines.
-molecular formula: C5H3D5NO3
-relative molecular mass: 129.17g/mol
-Appearance: White crystal or crystalline powder
-Melting point: 163-166 ° C
-Soluble: Soluble in water and ethanol
5-Oxo-DL-proline-d5 is commonly used as a labeling reagent in nuclear magnetic resonance (NMR) research to label and track the reaction and metabolism of compounds in biological systems. Due to its stable isotope labeling (embedding of heavy Hydrin D) and clear response in NMR spectrum, 5-Oxo-DL-proline-d5 is widely used in drug research and development, biochemistry, metabolomics and other fields.
The preparation method of 5-Oxo-DL-proline-d5 can be synthesized from natural products or synthetic compounds. A common preparation method is as follows:
1. First, select an appropriate starting compound, such as L-glutamic acid (L-Glutamic acid).
2. In a suitable solvent, the starting compound and heavy water reagent reaction. Common heavy hydrating reagents include heavy water or sodium deuterium oxide (D2O/NaOD).
3. Adjust the reaction conditions, such as temperature and reaction time, to convert the compound into 5-oxo-d1-proline-d5.
4. Finally, the target product is purified and harvested through the steps of crystallization, washing and drying.
In terms of safety, 5-Oxo-DL-proline-d5 has not been reported to be toxic or fatal. However, as an organic compound, normal laboratory safety practices should generally be followed, including wearing appropriate personal protective equipment (such as gloves, goggles, etc.) to avoid contact with skin and eyes, avoid inhalation or ingestion. In case of accidental splashing or contact, rinse immediately with plenty of water. In case of doubt or emergency, seek medical help immediately, consult the relevant agencies and follow the safe operation guidelines.
Last Update：2024-04-09 21:01:54
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Spot supply
Product Name: DL-Pyroglutamic acid-d5 Visit Supplier Webpage Request for quotationCAS: 352431-30-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 5-Oxo-DL-proline-d5 Visit Supplier Webpage Request for quotation
CAS: 352431-30-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 352431-30-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
(Pyrroglutamic Acid)
2-甲氧基氰乙酸乙酯
4,4-(-(1-甲基亚乙基)二[2-(2-丙烯基)]酚
异噻唑-3-基甲醇
3,5-DICHLOROBENZOIC ACID SOLUTION 100UG/ML IN ACETONITRILE 1ML
4-(4-吗啉代)苯胺
利伐沙班杂质P2-S
氟美他酚杂质8
硫酸镍,七水
Acetaldehyde, 2-(3,5,5-trimethyl-2-cyclohexen-1-ylidene)-, (2E)-
2-甲氧基氰乙酸乙酯
4,4-(-(1-甲基亚乙基)二[2-(2-丙烯基)]酚
异噻唑-3-基甲醇
3,5-DICHLOROBENZOIC ACID SOLUTION 100UG/ML IN ACETONITRILE 1ML
4-(4-吗啉代)苯胺
利伐沙班杂质P2-S
氟美他酚杂质8
硫酸镍,七水
Acetaldehyde, 2-(3,5,5-trimethyl-2-cyclohexen-1-ylidene)-, (2E)-