Molecular Formula | C22H19NO3 |
Molar Mass | 345.39 |
Storage Condition | -20℃ |
In vitro study | HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5); HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.895 ml | 14.476 ml | 28.953 ml |
5 mM | 0.579 ml | 2.895 ml | 5.791 ml |
10 mM | 0.29 ml | 1.448 ml | 2.895 ml |
5 mM | 0.058 ml | 0.29 ml | 0.579 ml |