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(E)-4-(6-甲氧基-2-(3-硝基苯乙烯基)-4-氧代喹唑啉-3(4H)-基)苯甲酸

4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic Acid

CAS: 1237744-13-6

Molecular Formula: C24H17N3O6

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(E)-4-(6-甲氧基-2-(3-硝基苯乙烯基)-4-氧代喹唑啉-3(4H)-基)苯甲酸 - Names and Identifiers

Name 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic Acid
Synonyms QNZ46
QNZ-46
QNZ 46
CS-2059
4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic Acid
CAS 1237744-13-6
EINECS 604-604-1

(E)-4-(6-甲氧基-2-(3-硝基苯乙烯基)-4-氧代喹唑啉-3(4H)-基)苯甲酸 - Physico-chemical Properties

Molecular FormulaC24H17N3O6
Molar Mass443.41
Density1.37±0.1 g/cm3(Predicted)
Melting Point>260 °C
Boling Point705.8±70.0 °C(Predicted)
Solubility DMSO: soluble5mg/mL (warmed; clear solution)
AppearanceYellow powder
Colorwhite to beige
pKa4.28±0.10(Predicted)
Storage ConditionSealed in dry,Room Temperature

(E)-4-(6-甲氧基-2-(3-硝基苯乙烯基)-4-氧代喹唑啉-3(4H)-基)苯甲酸 - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk Codes22 - Harmful if swallowed
WGK Germany3

(E)-4-(6-甲氧基-2-(3-硝基苯乙烯基)-4-氧代喹唑啉-3(4H)-基)苯甲酸 - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.255 ml11.276 ml22.552 ml
5 mM0.451 ml2.255 ml4.51 ml
10 mM0.226 ml1.128 ml2.255 ml
5 mM0.045 ml0.226 ml0.451 ml
Last Update:2024-01-02 23:10:35

(E)-4-(6-甲氧基-2-(3-硝基苯乙烯基)-4-氧代喹唑啉-3(4H)-基)苯甲酸 - Reference Information

biological activity QNZ46 is a NR2C/NR2D selective NMDA receptor antagonist (acting on NR2D, NR2C, NR2A, NR2B, and GluR1, IC50 values are 3, 6, 229, >300, >300 μM respectively).
Last Update:2024-04-09 20:49:11
(E)-4-(6-甲氧基-2-(3-硝基苯乙烯基)-4-氧代喹唑啉-3(4H)-基)苯甲酸
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CAS: 1237744-13-6
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CAS: 1237744-13-6
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MedChemExpress (MCE)
Spot supply
Product Name: QNZ46 Visit Supplier Webpage Request for quotation
CAS: 1237744-13-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: QNZ46 Visit Supplier Webpage Request for quotation
CAS: 1237744-13-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: QNZ46  Visit Supplier Webpage Request for quotation
CAS: 1237744-13-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic Acid Visit Supplier Webpage Request for quotation
CAS: 1237744-13-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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