(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione - Names and Identifiers
Name | 5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S)-
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Synonyms | Amrubicin intermediate Amrubicin Intermediate 5 Amrubicinhydrochloride int5 (+)-9-AMINO-4-DEMETHOXY-9-DEOXO-DAUNOMYCINONE 9α-amino-9β-acetyl-7,8,9,10-tetrahydro-6,7α,11-trihydroxy-5,12-naphthacenedione (7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione 5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S)-
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CAS | 92395-41-0
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(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione - Physico-chemical Properties
Molecular Formula | C20H17NO6
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Molar Mass | 367.35 |
Density | 1.550±0.06 g/cm3(Predicted) |
Melting Point | 158-159℃ |
Boling Point | 604.6±55.0 °C(Predicted) |
pKa | 7.92±0.60(Predicted) |
Use | Intermediate |
(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione - Introduction
5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S)-is an organic compound with the chemical name 5,12-Naphthacenedione, 9-acetyl-9-amino -6, 8,9-amino -6, 11-7, 10-7, 9-. Its chemical formula is C17H15NO5 and its molecular weight is 317.31.
5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S)-has important applications in the field of medicine. It is an antibiotic that belongs to the anthracycline class of compounds. It has anti-tumor activity and is commonly used in the treatment of various cancers, such as breast cancer, colorectal cancer, lung cancer, etc. It can inhibit the growth and division of tumor cells by inhibiting DNA synthesis and interfering with DNA replication.
The preparation method of 5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S)-is generally obtained by chemical synthesis. The specific synthesis method can be designed and optimized according to the specific process conditions.
Pay attention to safety when using 5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S). It is a toxic compound that is harmful to the human body and the environment. During handling and contact, care must be taken to wear appropriate personal protective equipment, such as laboratory gloves, goggles, etc. At the same time, treatment and disposal must be carried out in accordance with relevant laws and regulations to avoid pollution and harm to the environment. In terms of use, storage and waste disposal, the relevant safety operation procedures must be followed.
Last Update:2024-04-09 21:11:58