(4R,5R)-(-)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(P-TOSYL)BUTANE - Names and Identifiers
Name | (4S-trans)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethyl bis(toluene-p-sulphonate)
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Synonyms | (-)-1,4-Ditosyl-2,3,O-isopropylidene-L-threitol (-)-2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol (2S,3S)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol (4S,5S)-4,5-BIS(TOSYLOXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE (4S,5S)-(-)-4,5-BIS(TOSYLOXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE (4R,5R)-(-)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(P-TOSYL)BUTANE (4S,5S)-(+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(P-TOSYL)BUTANE (4S-trans)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethyl bis(toluene-p-sulphonate) (2,2-dimethyl-1,3-dioxolane-4,5-diyl)dimethanediyl bis(4-methylbenzenesulfonate) [(4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]dimethanediyl bis(4-methylbenzenesulfonate)
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CAS | 37002-45-2
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EINECS | 253-306-3 |
InChI | InChI=1/C21H26O8S2/c1-15-5-9-17(10-6-15)30(22,23)26-13-19-20(29-21(3,4)28-19)14-27-31(24,25)18-11-7-16(2)8-12-18/h5-12,19-20H,13-14H2,1-4H3 |
(4R,5R)-(-)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(P-TOSYL)BUTANE - Physico-chemical Properties
Molecular Formula | C21H26O8S2
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Molar Mass | 470.56 |
Density | 1.3082 (rough estimate) |
Melting Point | 90-92°C(lit.) |
Boling Point | 542.03°C (rough estimate) |
Flash Point | 321.7°C |
Solubility | DCM, Ethyl Acetate |
Vapor Presure | 4.31E-14mmHg at 25°C |
Appearance | Powder |
Color | white |
BRN | 99610 |
Storage Condition | Sealed in dry,2-8°C |
Stability | store cold |
Refractive Index | 1.6000 (estimate) |
MDL | MFCD00003212 |
(4R,5R)-(-)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(P-TOSYL)BUTANE - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
(4R,5R)-(-)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(P-TOSYL)BUTANE - Introduction
(4S-trans)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethyl bis(toluene-p-sulphonate) is an organic compound also known as (4S-trans)-2,2-dimethyl -1,3-dioxane-4, 5-dimethylbis-p-toluenesulfonate. Its structural formula is: dextrorotatory 1,4-di-O-methylglycitol is substituted by two tosylate groups in the 2,3-isopropylidene position.
Nature:
(4S-trans)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethyl bis(toluene-p-sulphonate) is a colorless crystalline solid with high melting point and good solubility. It is soluble in organic solvents and less soluble in water.
Use:
The compound is mainly used as an intermediate in organic synthesis for the synthesis of other compounds. It is widely used in pharmaceutical synthesis, pesticide synthesis, cosmetics and coatings and other fields.
Preparation Method:
The synthesis method of
(4S-trans)-2,2-dimethyl-1, 3-dioxolane-4, 5-dimethy1 bis(toluene-p-sulphonate) is relatively complex and is generally carried out through multi-step reactions. For specific synthesis routes, please refer to relevant professional literature.
Safety Information:
There is limited safety information about this compound, so use and handling should be in accordance with relevant laboratory practices and take effective personal protective measures, such as wearing appropriate protective gloves, eye protection and chemical protective clothing. At the same time, avoid inhaling its dust or vapor, and maintain good ventilation conditions. If contact or misuse occurs, seek medical help immediately.
Last Update:2024-04-09 21:11:58