(3-amino-6-nitro-1-benzofuran-2-yl)-(4-chlorophenyl)methanone - Names and Identifiers
(3-amino-6-nitro-1-benzofuran-2-yl)-(4-chlorophenyl)methanone - Physico-chemical Properties
Molecular Formula | C15H9ClN2O4
|
Molar Mass | 316.7 |
Density | 1.504g/cm3 |
Melting Point | 262°C (dec.)(lit.) |
Boling Point | 558.2°C at 760 mmHg |
Flash Point | 291.4°C |
Vapor Presure | 1.71E-12mmHg at 25°C |
Refractive Index | 1.705 |
(3-amino-6-nitro-1-benzofuran-2-yl)-(4-chlorophenyl)methanone - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
(3-amino-6-nitro-1-benzofuran-2-yl)-(4-chlorophenyl)methanone - Introduction
() (4-chorophenyl) methanone is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: A yellow solid
-Molecular formula: C14H9ClN2O4
-Molecular weight: 308.68g/mol
-melting point: about 188-192 ℃
-Solubility: Slightly soluble in ethanol and dimethyl sulfoxide, insoluble in water
Use:
- (4-chroophenyl) methanone is an important intermediate in organic synthesis and can be used to synthesize other compounds.
-In the field of medicine, it is also used as a precursor of anti-tumor drugs, anti-inflammatory drugs and antiviral drugs.
Preparation Method:
(4-chlorophenyl)methanone can be prepared by the following method:
-First, with benzofuran as the starting material, nitro groups are introduced at the 2-and 6-positions through nitration.
-Then, 4-chlorobenzoyl chloride is reacted with 3-aminobenzofuran to generate (chlorophenyl)(4-chlorophenyl)methanone.
Safety Information:
- (4-chorophenyl) methanone are organic compounds and are generally dangerous.
-When using or handling the compound, follow chemical safety practices, including wearing appropriate protective equipment (e. g. gloves, goggles, protective clothing).
-the compound should be kept away from the fire and oxidant, stored in a dry, cool place, avoid contact with acid, alkali material.
-In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical assistance.
Last Update:2024-04-09 21:01:54