(2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate
3-Iodo-L-tyrosine
CAS: 70-78-0
Molecular Formula: C9H10INO3
(2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate - Names and Identifiers
| Name | 3-Iodo-L-tyrosine |
| Synonyms | H-3-I-Tyr-Oh 3-I-L-Tyr-OH Iodotyrosine H-Tyr(3-I)-Oh H-Tyr(M-I)-Oh H-3-Iodo-Tyr-Oh H-L-Tyr(3-I)-Oh 3-Iodo-Tyrosine 3-Iodo-D-Tyrosine 3-Iodo-L-tyrosine H-3-I-Phe(4-Oh)-Oh L-TYROSINE, 3-IODO- L-Tyrosine, 3-Iodo- Tyrosine,3-Iodo-, L- H-L-Phe(3-I,4-OH)-OH 3-Monoiodo-L-Tyrosine 4-Hydroxy-3-iodophenylalanine 3-Iodo-4-hydroxyphenylalanine (2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate (S)-2-AMino-3-(4-hydroxy-3-iodophenyl)propanoic acid |
| CAS | 70-78-0 |
| EINECS | 200-744-8 |
| InChI | InChI=1/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m1/s1 |
| InChIKey | UQTZMGFTRHFAAM-ZETCQYMHSA-N |
(2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate - Physico-chemical Properties
| Molecular Formula | C9H10INO3 |
| Molar Mass | 307.09 |
| Density | 1.7280 (estimate) |
| Melting Point | 210°C (dec.)(lit.) |
| Boling Point | 391.0±42.0 °C(Predicted) |
| Flash Point | 190.3°C |
| Solubility | dilute aqueous acid: soluble |
| Vapor Presure | 8.18E-07mmHg at 25°C |
| Appearance | White solid |
| Color | White to off-white |
| Merck | 14,5047 |
| BRN | 2941266 |
| pKa | 2.21±0.20(Predicted) |
| Storage Condition | -20°C |
| Stability | Hygroscopic |
| Sensitive | Light Sensitive |
| Refractive Index | 1.688 |
| MDL | MFCD00002608 |
| Physical and Chemical Properties | Melting Point 210°C (dec.)(lit.) Storage Conditions 2-8°C solubility dilute aquatic acid: soluble Merck 5047 |
| Use | Tyrosine hydroxylase inhibitors. |
| In vitro study | H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%. |
(2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10-23 |
| HS Code | 29225090 |
(2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate - Introduction
Dissolve in 15 parts of boiling water.
Last Update：2022-10-16 17:28:03
(2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is responsible for catalyzing the first step in the norepinephrine biosynthetic pathway. H-Tyr(3-I)-OH is a potent tyrosinase inhibitor. |
Last Update：2024-04-09 15:16:52
Supplier List
Spot supply
Product Name: H-Tyr(3-I)-OH Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: H-Tyr(3-I)-OH Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3-Iodo-L-tyrosine Visit Supplier Webpage Request for quotationCAS: 70-78-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
(2S)-2-ammonio-3-(4-hydroxy-3-iodophenyl)propanoate
二乙基甲基一氢硅烷
(4R,5R)-1-Azabicyclo[3.3.0]octane-4-carboxylic acid methyl ester
Benzenamine, N-[3,5-bis(1,1-dimethylethyl)phenyl]-2,4,6-trinitro-
2-(Pyridin-2-yl)propan-2-amine
2-(3-Isopropoxyphenyl)ethan-1-ol
2-(2-环丙基丙-1-烯-1-基)-4,4,5,5-四甲基-1,3,2-二氧杂硼烷
1-(4-Piperidinyloxy)-2-propanol
2-Hydroxy-4-methyl-2H-furan-5-one
二乙基甲基一氢硅烷
(4R,5R)-1-Azabicyclo[3.3.0]octane-4-carboxylic acid methyl ester
Benzenamine, N-[3,5-bis(1,1-dimethylethyl)phenyl]-2,4,6-trinitro-
2-(Pyridin-2-yl)propan-2-amine
2-(3-Isopropoxyphenyl)ethan-1-ol
2-(2-环丙基丙-1-烯-1-基)-4,4,5,5-四甲基-1,3,2-二氧杂硼烷
1-(4-Piperidinyloxy)-2-propanol
2-Hydroxy-4-methyl-2H-furan-5-one