(2R,3R,4R,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-3,4-diol - Names and Identifiers
Name | 6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine
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Synonyms | 6-Chloro-9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine 6-CHLORO-9-(2-METHYL-BETA-D-RIBOFURANOSYL)-9H-PURINE 9H-Purine, 6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)- 6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine 9H-purine, 6-chloro-9-(2-C-methyl-beta-D-ribofuranosyl)- (2R,3R,4R,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-3,4-diol
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CAS | 205171-05-7
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InChI | InChI=1/C11H13ClN4O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3/t5-,7-,10-,11-/m1/s1 |
(2R,3R,4R,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-3,4-diol - Physico-chemical Properties
Molecular Formula | C11H13ClN4O4
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Molar Mass | 300.7 |
Density | 1.86 |
Boling Point | 590.081°C at 760 mmHg |
Flash Point | 310.67°C |
Vapor Presure | 0mmHg at 25°C |
Storage Condition | Room Temprature |
Refractive Index | 1.779 |
(2R,3R,4R,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-3,4-diol - Introduction
6-Chloro-9-()-9H-purine, abbreviated as 6-chloro-mpp, is an organic compound. Its nature, use, formulation and safety information are described below.
Nature:
6-Chloro-mpp is a white crystalline solid with chemical stability. It has a forced substitution effect, can combine with DNA, inhibit nucleic acid synthesis, thus affecting the normal function of cells.
Use:
6-chloro-mpp is an important anti-tumor drug and belongs to a class of anti-metabolic anti-cancer drugs. It can inhibit the DNA synthesis and RNA synthesis of cancer cells, prevent the growth and reproduction of cancer cells, so as to play an anti-tumor effect.
Method:
The preparation method of 6-chloro-mpp is more complicated, and is generally synthesized by organic synthesis methods. The preparation process requires high-purity raw materials and a series of organic reactions, including substitution reactions, acylation reactions, and reduction reactions. For specific synthetic steps, reference may be made to relevant organic synthesis literature or patent data.
Safety Information:
According to relevant research, 6-chloro-mpp is relatively safe for short-term use in laboratory and clinical treatment. However, factors such as dose, method of use, and individual differences can affect the safety and toxicological profile of a drug. In the use of the substance, should be strictly in accordance with the doctor's advice, and comply with the relevant drug management norms. In addition, attention should be paid to the reasonable storage and disposal of drugs to prevent pollution to the environment and damage to human health. For specific information on the toxicity and safety of the substance, reference should be made to the relevant studies and product specifications.
Last Update:2024-04-09 02:00:44