(2-氨基-4-(异丙氧基羰基)苯基)硼酸盐酸盐 - Names and Identifiers
(2-氨基-4-(异丙氧基羰基)苯基)硼酸盐酸盐 - Physico-chemical Properties
Molecular Formula | C10H15BClNO4
|
Molar Mass | 259.49 |
Storage Condition | Sealed in dry,Room Temperature |
Sensitive | Irritant |
MDL | MFCD12025975 |
(2-氨基-4-(异丙氧基羰基)苯基)硼酸盐酸盐 - Introduction
(2-Amino-4-(isopropoxycarbonyl)phenyl)-boronic acid hydrochloride is an organic compound whose chemical formula is C11H16BNO4Cl. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow solid
-Solubility: Soluble in water and most organic solvents
-Melting point: about 160-165°C
-Molecular weight: about 273.6g/mol
Use:
- (2-Amino-4-(isopropoxycarbonyl)phenyl)-boronic acid hydrochloride is an important organic synthesis intermediate, often used in organic synthesis reactions.
-It can be used to construct boron-containing organic compounds, and can be applied to Suzuki coupling reactions and other cross-coupling reactions.
-can be used for the synthesis of organic fluorescent dyes and inorganic materials.
Preparation Method:
The preparation method of
(2-Amino-4-(isopropoxycarbonyl)phenyl)-boronic acid hydrochloride is more complicated. The following is a commonly used synthetic route:
1.2-amino -4-hydroxy benzoic acid and isopropyl alcohol were esterified to obtain isopropyl 2-amino -4-(isopropoxycarbonyl) benzoate.
2. Suzuki coupling reaction was carried out between isopropyl 2-amino -4-(isopropoxycarbonyl) benzoate and triphenylphosphine succinate palladium (II) catalyst to generate the target product (2-Amino-4-(isopropoxycarbonyl)phenyl)-boronic acid hydrochloride.
Safety Information:
(2-Amino-4-(isopropoxycarbonyl)phenyl)-boronic the acid hydrochloride is relatively stable under normal conditions, the following safety precautions should be paid attention:
-Avoid contact with oxidizing agents to avoid dangerous reactions.
-Avoid inhaling dust, contact with skin and eyes.
-During use, follow laboratory safety procedures and wear appropriate personal protective equipment, such as gloves, goggles and laboratory clothing.
-In case of accidental contact or inhalation, rinse immediately with water or carry to a medical institution for treatment.
It should be emphasized that when using this compound for experiments or synthesis, please ensure that you operate under safe and well-controlled laboratory conditions and follow appropriate safe operating procedures.
Last Update:2024-04-10 22:29:15