Molecular Formula | C18H27NO2 |
Molar Mass | 289.41 |
Density | 1.029±0.06 g/cm3(Predicted) |
Boling Point | 447.8±28.0 °C(Predicted) |
JECFA Number | 2079 |
Solubility | DMSO: >20mg/mL |
Vapor Presure | 0-0Pa at 20-50℃ |
Appearance | White to off-white powder. |
Color | white to off-white |
pKa | 14.18±0.70(Predicted) |
Storage Condition | -20°C |
Hazard Symbols | N - Dangerous for the environment |
Risk Codes | 50 - Very Toxic to aquatic organisms |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3077 9 / PGIII |
FEMA | 4681 | (1R,2S,5R)-N-(4-METHOXYPHENYL)-5-METHYL-2-(1-METHYLETHYL)CYCLOHEXANECARBOXAMIDE |
LogP | 3.95 at 22℃ and pH7.7 |
use | WS-12 has mint-like cool taste, and can be used as a cool taste enhancer for oral care, chewing gum and children's sugar. It can also be used as a cooler for skin and lipstick. |
biological activity | WS-12 is an agonist of TRPM8 with an EC50 value of 39 nM. |
target | EC50: 39 nM (TRPM8) |