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(1-氰基-2-乙氧基-2-氧代亚乙基氨基氧基)二甲基氨基吗啉代碳鎓六氟磷酸盐

4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium

CAS: 1075198-30-9

Molecular Formula: C12H19F6N4O4P

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  4. (1-氰基-2-乙氧基-2-氧代亚乙基氨基氧基)二甲基氨基吗啉代碳鎓六氟磷酸盐

(1-氰基-2-乙氧基-2-氧代亚乙基氨基氧基)二甲基氨基吗啉代碳鎓六氟磷酸盐 - Names and Identifiers

Name 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium
Synonyms elagolix intermediate 13
(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate
4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate
1-[1-(Cyano-2-ethoxy-2-oxoethylideneaMinooxy)-diMethylaMino-Morpholino]-uroniuM hexafluorophosphate
{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxy}dimethylamino(morpholin-4-yl)carbenium hexafluorophosp
4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium
4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium(COMU?)
(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.)
CAS 1075198-30-9
EINECS 682-899-5

(1-氰基-2-乙氧基-2-氧代亚乙基氨基氧基)二甲基氨基吗啉代碳鎓六氟磷酸盐 - Physico-chemical Properties

Molecular FormulaC12H19F6N4O4P
Molar Mass428.2678402
Melting Pointca 160℃
Solubility Soluble in DMF 1mmol in 2mL.
AppearancePowder or Solid
ColorWhite to pale yellow
Storage ConditionStore at -15°C to -25°C.
SensitiveAir & Moisture Sensitive

(1-氰基-2-乙氧基-2-氧代亚乙基氨基氧基)二甲基氨基吗啉代碳鎓六氟磷酸盐 - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany3
HS Code2934 99 90

(1-氰基-2-乙氧基-2-氧代亚乙基氨基氧基)二甲基氨基吗啉代碳鎓六氟磷酸盐 - Reference Information

Use (ethyl 2-oxime-cyanoacetate)-N,N-dimethyl-morpholino urea hexafluorophosphate, also known as COMU, is a polypeptide condensation reagent, which is mainly used in the synthesis of polypeptide drug molecules and is widely used in solid phase and liquid phase.
compared with the traditional first-generation condensation reagents (carbodiimides) represented by DCC and the second-generation condensation reagents (onium salts) represented by HATU, COMU has better solubility, stability, reactivity, low risk and low sensitivity to the human body; At the same time, the by-products generated are easily soluble in water and can be removed well, so the synthesis of COMU polypeptide drug molecules, especially in the solid phase synthesis of more obvious advantages.
Last Update:2024-04-10 22:29:15
(1-氰基-2-乙氧基-2-氧代亚乙基氨基氧基)二甲基氨基吗啉代碳鎓六氟磷酸盐
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Suzhou Haofan biological Co., Ltd.
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Product Name: 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium Request for quotation
CAS: 1075198-30-9
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CAS: 1075198-30-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Suzhou Haofan biological Co., Ltd.
Featured Products
Product Name: 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium Request for quotation
CAS: 1075198-30-9
Tel: +86 0512-68417696
Email: chenmengqi@highfine.com
     wuhao@highfine.com
     merry@highfine.com
QQ: 4006286883 Click to send a QQ message
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: COMU Visit Supplier Webpage Request for quotation
CAS: 1075198-30-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: COMU Visit Supplier Webpage Request for quotation
CAS: 1075198-30-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: COMU Visit Supplier Webpage Request for quotation
CAS: 1075198-30-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: COMU Visit Supplier Webpage Request for quotation
CAS: 1075198-30-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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