(1,2-dimethyl-1H-imidazol-5-yl)methanamine - Names and Identifiers
(1,2-dimethyl-1H-imidazol-5-yl)methanamine - Physico-chemical Properties
Molecular Formula | C6H11N3
|
Molar Mass | 125.17 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD18071367 |
(1,2-dimethyl-1H-imidazol-5-yl)methanamine - Risk and Safety
(1,2-dimethyl-1H-imidazol-5-yl)methanamine - Introduction
The compound 1-(1,2-dimethyl -1H-imidazol-5-yl) methanamine, the chemical formula is [(1, 2-dimethyl) methyl 1] aminedihydrochloride, abbreviated as DMIM. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: DMIM is a white crystalline solid.
-Melting point: The melting point of DMIM is about 110-112°C.
-Solubility: DMIM is easily soluble in water with a solubility of about 250 mg/mL.
-Acid and alkaline: DMIM is a weak base, and its solution is alkaline.
Use:
-Catalyst: DMIM is often used as a catalyst in organic synthesis to participate in various organic reactions, such as aldehyde condensation synthesis, Michael addition and other C- C and C- N bond building reactions.
-Pharmaceutical intermediates: DMIM can be used to synthesize biologically active compounds, such as drugs in the pharmaceutical field.
-Coordination ligand: DMIM is often used as a ligand to form a coordination compound with a transition metal.
Preparation Method:
The preparation of DMIM can be carried out by the following steps:
1. Synthesis of 1,2-dimethyl -1H-imidazole:
-Reaction of dimethylamine and formaldehyde by heating to obtain 1,2-dimethyl-1H-imidazole.
2. Synthesis of 1-(1,2-dimethyl-1H-imidazol-5-yl) methylamine:
-1,2-dimethyl-1H-imidazole is added to ethanol and reacted with methyl sulfoxide chloride to obtain 1-(1,2-dimethyl-1H-imidazol-5-yl) methanamine.
3. Get [(1, +) methyl]aminedihydrochloride:
-Reaction of 1-(1,2-dimethyl-1H-imidazol-5-yl) methanamine with hydrochloric acid to obtain [(1,) methyl]aminedihydrochloride.
Safety Information:
- DMIM is a common chemical in laboratory and industrial settings that requires proper storage and use.
- DMIM is irritating and may cause irritation to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as gloves, goggles and face shields during operation.
-Care should be taken to control exposure and avoid inhalation, skin contact and ingestion during use.
-If exposed to or inhaled DMIM, rinse immediately with plenty of water and seek medical help.
Please note that when using any chemical, follow the correct operating procedures and read the safety information and operating instructions provided with the chemical carefully.
Last Update:2024-04-09 20:49:11