中文名 | 辛夷脂素 |
英文名 | fargesin |
别名 | 辛胰脂素 辛夷脂素 发式玉兰素 发氏玉兰素 辛夷脂素对照品, 辛夷脂素(发式玉兰素) DEMETHOXYASCHANTIN 辛夷脂素 |
英文别名 | fargesin FARGESIN Methyl pluviatilol (1β,5β)-2α-(3,4-Dimethoxyphenyl)-6β-(1,3-benzodioxole-5-yl)-3,7-dioxabicyclo[3.3.0]octane (1S,3aβ,6aβ)-1β-(1,3-Benzodioxole-5-yl)-4α-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan 5-[(1β,3aβ,4α,6aβ)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole 5-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole 1,3-benzodioxole, 5-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]- rel-5-[(1R,3aS,4S,6aS)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole (1R)-4β-(1,3-Benzodioxole-5-yl)-3aβ,4,6,6aβ-tetrahydro-1α-(3,4-dimethoxyphenyl)-1H,3H-furo[3,4-c]furan 1,3-Benzodioxole,5-[(1R,3aS,4S,6aS)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-,rel- |
CAS | 31008-19-2 |
化学式 | C21H22O6 |
分子量 | 370.4 |
InChI | InChI=1/C21H22O6/c1-22-16-5-3-12(7-18(16)23-2)20-14-9-25-21(15(14)10-24-20)13-4-6-17-19(8-13)27-11-26-17/h3-8,14-15,20-21H,9-11H2,1-2H3/t14-,15-,20-,21+/m0/s1 |
密度 | 1.265±0.06 g/cm3(Predicted) |
熔点 | 132.0 to 136.0 °C |
沸点 | 506.4±50.0 °C(Predicted) |
闪点 | 208.923°C |
蒸汽压 | 0mmHg at 25°C |
溶解度 | 可溶于苯、DMSO等溶剂。 |
折射率 | 1.58 |
存储条件 | 2-8°C |
外观 | 无色晶体 |
物化性质 | 白色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于辛夷,望春玉兰花蕾。 |
MDL号 | MFCD28989184 |
体外研究 | Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB. Fargesin as a potential β₁ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis. |
体内研究 | Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release. |
参考资料 展开查看 | 1. Guang Yang, Xin Zhao, Guorong Fan,A modification on the vector cosine algorithm of Similarity Analysis for improved discriminative capacity and its application to the quality control of Magnoliae Flos,Journal of Chromatography A,Volume 1518,2017,Pages 2. [IF=4.759] Guang Yang et al."A modification on the vector cosine algorithm of Similarity Analysis for improved discriminative capacity and its application to the quality control of Magnoliae Flos."J Chromatogr A. 2017 Oct;1518:34 |