中文名 | 磷酸二酯酶 |
英文名 | phosphodiesterase I type vii from crotalus atrox |
别名 | 硅磷晶 磷酸二脂酶 磷酸二酯酶 磷酸二酯酶I 5-磷酸二酯酶 |
英文别名 | 5-EXONUCLEASE PHOSPHODIESTERASE I 5-EXONUCLEASE TYPE V 5-EXONUCLEASE TYPE IV phosphodiesterase I type vii from crotalus atrox phosphodiesterase I from bovine intestinal mucosa |
CAS | 9025-82-5 |
EINECS | 232-806-5 |
存储条件 | -20°C |
外观 | 粗干毒液 |
产品用途 | Venom exonuclease (Phosphodiesterase I) successively hydrolyzes 5'-mononucleotides from 3'-OH-terminated ribo- and deoxyribo-oligonucleotides. The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. Phosphodiesterase is inhibited by reducing agents such as glutathione, cysteine and ascorbic acids. It is completely inhibited by 5mM EDTA while ATP, ADP and AMP are partial inhibitors. The enzyme has an absolute requirement for Mg2+ |
MDL号 | MFCD00131883 |
危险品标志 | T+ - 极高毒性物品 |
风险术语 | 26/27/28 - 吸入、皮肤接触及吞食有极高毒性。 |
安全术语 | S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 |
危险品运输编号 | 2811 |
WGK Germany | 3 |
RTECS | SZ5999500 |
Hazard Class | 6.1(a) |
Packing Group | II |
下游产品 | 6-硫鸟嘌呤 肌苷酸二钠 5-腺苷酸 脱氧核苷酸 |
参考资料 展开查看 | 1. 柴洋洋, 王雨萱, 艾凯,等. 茶树菇呈味物质的提取及鲜味剂的研究[J]. 中国调味品, 2020, v.45;No.493(03):8-13+17. 2. [IF=2.629] Liu Zichen et al."Rapid Screening of Potential Phosphodiesterase Inhibitors from the Roots of Ilex pubescens Hook. et Arn. Using a Combination of Ultrafiltration and LC–MS."Evid-Based Compl Alt. 2017;2017:2749643 3. [IF=4.142] Qu Fei et al."Ratiometric detection of alkaline phosphatase based on aggregation-induced emission enhancement."Anal Bioanal Chem. 2019 Nov;411(28):7431-7440 |