中文名 | 物质P片段1-7 |
英文名 | substance P fragment 1-7 |
别名 | P物质片段1-7 1-7-P 物质 物质P片段1-7 |
英文别名 | RPKPQQF SUBSTANCE P (1-7) Substance P (1-7) substance P fragment 1-7 SUBSTANCE P FRAGMENT 1-7 ARG-PRO-LYS-PRO-GLN-GLN-PHE H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-OH L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-OH L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-OH |
CAS | 68060-49-1 |
化学式 | C41H65N13O10 |
分子量 | 900.04 |
密度 | 1.49±0.1 g/cm3(Predicted) |
酸度系数 | 3.49±0.10(Predicted) |
存储条件 | −20°C |
MDL号 | MFCD00076789 |
体内研究 | Substance P (1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P (1-7) is an endogenous modulator of SP actions. Injection of low doses of Substance P (1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord. |
WGK Germany | 3 |
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