中文名 | 澳洲茄碱 |
英文名 | Solasonine |
别名 | 茄解碱 澳洲茄碱 奥洲茄碱 羥基茄鹼 澳洲茄鹼 澳州茄碱 澳洲茄碱(标准品) Α-澳洲茄碱,茄解碱 |
英文别名 | PURAPURIN NSC 82149 Solasonin PURAPURINE SOLANINE S Solasonine SOLANCARPIN SOLASODAMINE alpha-Solasonine Tomatine solaradixine Solasonine 19121-58-5 Solasoninealpha-Solasonine beta-D-Galactopyranoside, (3beta,22alpha,25R)-spirosol-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))- (9CI) |
CAS | 19121-58-5 1369-76-2 28701-66-8 77-34-9 |
EINECS | 242-826-6 |
化学式 | C45H73NO16 |
分子量 | 884.07 |
InChI | InChI=1/C45H73NO16/c1-19-8-13-45(46-16-19)20(2)30-27(62-45)15-26-24-7-6-22-14-23(9-11-43(22,4)25(24)10-12-44(26,30)5)57-42-39(61-40-36(54)34(52)31(49)21(3)56-40)38(33(51)29(18-48)59-42)60-41-37(55)35(53)32(50)28(17-47)58-41/h6,19-21,23-42,46-55H,7-18H2,1-5H3/t19-,20+,21+,23+,24-,25+,26+,27+,28-,29-,30+,31+,32-,33+,34-,35+,36-,37-,38+,39-,40+,41+,42-,43+,44+,45-/m1/s1 |
密度 | 1.42 |
熔点 | 301-303℃ |
比旋光度 | D23 -88° (c = 1.01 in pyridine); D22 -74.5° (c = 0.51 in methanol) |
溶解度 | 溶于热乙醇和热二氧六环,微溶于热水和稀醋酸,不溶于氯仿和乙醚。 |
折射率 | 1.627 |
酸度系数 | 12.78±0.70(Predicted) |
存储条件 | 2-8℃ |
外观 | 为针状结晶 |
物化性质 | 溶于热乙醇和热二氧六环,微溶于热水和稀醋酸,不溶于氯仿和乙醚。 来源于茄科植物澳洲茄(Solanum aviculare Forst.)的果实 |
MDL号 | MFCD00017611 |
参考资料 展开查看 | 1. 高洁 朱名毅 黄祖良 等. RP-HPLC测定水茄果实不同提取物中澳洲茄碱含量[J]. 中国实验方剂学杂志 2014 20(17):46-48. 2. [IF=4.411] Jun Yang et al."Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity."Molecules. 2016 Oct;21(10):1364 3. [IF=3.266] Xun Wang et al."Solasonine inhibits glioma growth through anti-inflammatory pathways."Am J Transl Res. 2017; 9(9): 3977–3989 4. [IF=6.244] Hong Zhang et al."Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis."Front Oncol. 2021 Jan 29;10:614067 5. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150 |