中文名 | 乙酰胆碱酯酶 |
英文名 | Anticholinesterase |
别名 | 乙酰胆碱酯酶 胆碱酯酶乙酰化 乙酰胆碱酯酶 来源于电鳗鱼 乙酰胆碱酯酶 来源于苍蝇头部 |
英文别名 | ACHE Anticholinesterase TRUE CHOLINESTERASE Esterase, acetyl choline TRUE CHOLINESTERASE HUMAN TRUE CHOLINESTERASE TYPE V-S TRUE CHOLINESTERASE TYPE VI-S TRUE CHOLINESTERASE TYPE XII-S Acetylcholinesterase from electric eel ACETYLCHOLINESTERASE TYPE III ELECTRIC |
CAS | 9000-81-1 |
EINECS | 232-559-3 |
溶解度 | H2O: 1 mg/mL |
存储条件 | -20°C |
外观 | 粉末 |
颜色 | slightly yellow |
MDL号 | MFCD00081268 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
参考资料 展开查看 | 1. 曹婷婷 陈俊涛 杨春柳 田云锋 冯腾垒 马正月.4-吡啶基噻唑-2-胺衍生物的设计、合成及其对乙酰胆碱酯酶的抑制活性研究[J].药学学报 2016 51(09):1436-1440. 2. 巫川 王树涛 朱婧 尤宏.BDE-47和BDE-209对乙酰胆碱酯酶(AChE)活性的抑制特性及分子作用力研究[J].生态毒理学报 2017 12(06):99-106. 3. 于浩然 高翔 田振坤 等. 五味子各萃取物抗氧化作用及抑制乙酰胆碱酯酶活性研究[J]. 现代中药研究与实践 2017 031(004):33-36. 4. 郭明 梁东军 谭贤. 农药残留检测用新型碳纳米管固载酶生物传感器的制备及其电学传感性能分析[J]. 农药学学报 2014. 5. 伍周玲, 梁东军, 郭明,等. 新型固定化乙酰胆碱酯酶传感器的制备及氨基甲酸酯农残检测[J]. 浙江农林大学学报, 2014(3). 6. 伍周玲, 燕冰宇, 梁东军,等. 新型固载酶生物传感器制备及食品中有机磷农药检测[J]. 中国食品学报, 2015, 15(003):166-174. 7. 郭明,燕冰宇,周珊,王春鹏,储富祥.纤维素基固载酶材料的制备及乙酰胆碱酯酶的固定化性能[J].高分子材料科学与工程,2013,29(10):150-154+159. 8. 常艳兵,杨晓丽,何琼.铂钴合金修饰的乙酰胆碱酯酶生物传感器的研制铂钴合金修饰的乙酰胆碱酯酶生物传感器的研制[J].云南化工,2013,40(04):1-5. 9. 何忠梅,吕娜,南敏伦,赵昱玮,赫玉芳,孟令文,孙佳明,张连学.靶向亲和-液相色谱-质谱联用技术快速筛选黄藤总生物碱中乙酰胆碱酯酶抑制剂[J].分析化学,2017,45(02):211-216. 10. 邢志恒, 吕娜, 何忠梅,等. 黄藤素衍生物的合成及其抑制乙酰胆碱酯酶活性研究[J]. 分析化学, 2018, 46(005):684-689. 11. 韩岚 季兆洁 陈卫东 等. 四物汤对血管性痴呆大鼠的神经保护作用及其机制研究[J]. 安徽中医药大学学报 2015 34(4):69-73. 12. 罗琴, 祖云鸿, 石开琼,等. 微酸性电解水去除蔬菜农药残留效果的研究[J]. 食品安全质量检测学报, 2014(11):3657-3663. 13. 凌庆枝, 董丽辉, 范三微,等. 蛇足石杉体内抑制乙酰胆碱酯酶活性物质的内生真菌的分离[J]. 安徽农业科学, 2012(30):14706-14707. 14. 王焕南, 赵艳, 王向月,等. 日照海域牡蛎共生真菌的分离,鉴定及生物活性研究[J]. 济宁医学院学报, 2020(3):188-193. 15. 王焕南, 杨华, 顾英琳,等. 牡蛎共生细菌的分离,鉴定及次级代谢产物生物活性研究[J]. 聊城大学学报(自然科学版), 2019(5). 16. Zhai, Meng‐Yu, et al. "Development of a novel nano‐based detection card by electrospinning for rapid and sensitive analysis of pesticide residues." Journal of the Science of Food and Agriculture 100.12 (2020): 4400-4408.https://doi.org/10.1002/jsfa.10477 17. Qing, Z., Li, Y., Li, Y. et al. Thiol-suppressed I2-etching of AuNRs: acetylcholinesterase-mediated colorimetric detection of organophosphorus pesticides. Microchim Acta 187, 497 (2020). https://doi.org/10.1007/s00604-020-04486-2 18. Wang, X., Liu, Z., Zhao, W. et al. A novel switchable fluorescent sensor for facile and highly sensitive detection of alkaline phosphatase activity in a water environment with gold/silver nanoclusters. Anal Bioanal Chem 411, 1009–1017 (2019). https://doi.o 19. Zhang, Fangmei, et al. "Dopamine-modified Mn-doped ZnS quantum dots fluorescence probe for the sensitive detection of tyrosinase in serum samples and living cells imaging." Sensors and Actuators B: Chemical 256 (2018): 1069-1077.https://doi.org/10.1016/j.s 20. Longbin Xu, Xu He, Pinyi Ma, Xin Liu, Fangmei Zhang, Ying Sun, Daqian Song, Xinghua Wang,A water-soluble fluorescent probe for the sensitive detection of endogenous alkaline phosphatase in living cells,Dyes and Pigments,Volume 159,2018,Pages 584-589, 21. [IF=9.229] Li He et al."In Situ Synthesis of Gold Nanoparticles/Metal–Organic Gels Hybrids with Excellent Peroxidase-Like Activity for Sensitive Chemiluminescence Detection of Organophosphorus Pesticides."Acs Appl Mater Inter. 2018;10(34):28868–28876 22. [IF=7.1] Fangmei Zhang et al."Dopamine-modified Mn-doped ZnS quantum dots fluorescence probe for the sensitive detection of tyrosinase in serum samples and living cells imaging."Sensor Actuat B-Chem. 2018 Mar;256:1069 23. [IF=6.986] Yue Zhao et al."Detection of Various Biomarkers and Enzymes via a Nanocluster-Based Fluorescence Turn-on Sensing Platform."Anal Chem. 2018;90(24):14578–14585 24. [IF=5.833] Zhang Fangmei et al."Enzymatic determination of uric acid using water-soluble CuInS/ZnS quantum dots as a fluorescent probe."Microchim Acta. 2018 Nov;185(11):1-8 25. [IF=5.833] Dai Qingzhou et al."Adsorption and specific recognition of DNA by using imprinted polymer layers grafted onto ionic liquid functionalized magnetic microspheres."Microchim Acta. 2017 Nov;184(11):4433-4441 26. [IF=4.613] Longbin Xu et al."A water-soluble fluorescent probe for the sensitive detection of endogenous alkaline phosphatase in living cells."Dyes Pigments. 2018 Dec;159:584 27. [IF=4.379] Zhou Bohang et al."New 2-Aryl-9-methyl-β-carbolinium salts as Potential Acetylcholinesterase Inhibitor agents: Synthesis, Bioactivity and Structure–Activity Relationship."Sci Rep-Uk. 2018 Jan;8(1):1-18 28. [IF=4.372] Shutao Wang et al."Studies on the interaction of BDE-47 and BDE-209 with acetylcholinesterase (AChE) based on the neurotoxicity through fluorescence, UV–vis spectra, and molecular docking."Toxicol Lett. 2018 May;287:42 29. [IF=4.142] Wang Xiaoyan et al."A novel switchable fluorescent sensor for facile and highly sensitive detection of alkaline phosphatase activity in a water environment with gold/silver nanoclusters."Anal Bioanal Chem. 2019 Feb;411(5):1009-1017 30. [IF=7.46] Yue Zhang et al."A dual-signal sensing platform based on nanosheet materials for ratiometric fluorescence and colorimetric detection of enzyme activities in human blood."Sensor Actuat B-Chem. 2021 Nov;346:130531 31. [IF=6.986] Yue Hu et al."Dual-Mode Sensing Platform for Electrochemiluminescence and Colorimetry Detection Based on a Closed Bipolar Electrode."Anal Chem. 2021;93(36):12367–12373 32. [IF=6.514] Bohang Zhou et al."Simple analogues of natural product chelerythrine: Discovery of a novel anticholinesterase 2-phenylisoquinolin-2-ium scaffold with excellent potency against acetylcholinesterase."Eur J Med Chem. 2020 Aug;200:112415 33. [IF=5.833] Qing Zhihe et al."Thiol-suppressed I2-etching of AuNRs: acetylcholinesterase-mediated colorimetric detection of organophosphorus pesticides."Microchim Acta. 2020 Sep;187(9):1-9 34. [IF=4.616] Jiarui Yu et al."A photoelectrochemical sensor based on an acetylcholinesterase-CdS/ZnO-modified extended-gate field-effect transistor for glyphosate detection."Analyst. 2021 Jul;146(14):4595-4604 35. [IF=4.142] Qu Fei et al."Ratiometric detection of alkaline phosphatase based on aggregation-induced emission enhancement."Anal Bioanal Chem. 2019 Nov;411(28):7431-7440 36. [IF=3.638] Meng-Yu Zhai et al."Development of a novel nano-based detection card by electrospinning for rapid and sensitive analysis of pesticide residues."J Sci Food Agr. 2020 Sep;100(12):4400-4408 37. [IF=3.205] Hui-Peng Song et al."A strategy to discover lead chemome from traditional Chinese medicines based on natural chromatogram-effect correlation (NCEC) and natural structure-effect correlation (NSEC): Mahonia bealei and Mahonia fortunei as a case study."J Chr 38. [IF=4.952] Bailiang Zheng et al.Green extraction of phenolic compounds from foxtail millet bran by ultrasonic-assisted deep eutectic solvent extraction: Optimization, comparison and bioactivities.Lwt Food Sci Technol. 2022 Jan;154:112740 39. [IF=6.475] Tao-Tao Xue et al."Evaluation of antioxidant, enzyme inhibition, nitric oxide production inhibitory activities and chemical profiles of the active extracts from the medicinal and edible plant: Althaea officinalis."Food Res Int. 2022 Jun;156:111166 40. [IF=7.514] Huanyu Yang et al."Ultrasmall Au nanoparticles modified 2D metalloporphyrinic metal-organic framework nanosheets with high peroxidase-like activity for colorimetric detection of organophosphorus pesticides."Food Chem. 2022 May;376:131906 |