中文名 | HKOCL-4 |
英文名 | Spiro[6H-[1]benzopyrano[3,2-g]quinoline-6,1'(3'H)-isobenzofuran]-1(2H)-butanoic acid, 9-(3,5-dichloro-4-hydroxyphenoxy)-3,4-dihydro-2,2,4-trimethyl-3'-oxo-, ethyl ester |
英文别名 | BXY2142 HKOCl-4 HKOCL-4 Spiro[6H-[1]benzopyrano[3,2-g]quinoline-6,1'(3'H)-isobenzofuran]-1(2H)-butanoic acid, 9-(3,5-dichloro-4-hydroxyphenoxy)-3,4-dihydro-2,2,4-trimethyl-3'-oxo-, ethyl ester |
CAS | 2031170-85-9 |
化学式 | C38H35Cl2NO7 |
分子量 | 688.59 |
体外研究 | HKOCl-4 (10 μM) shows an increasing florescence intensity with increasing concentration of hypochlorous acid. HKOCl-4 exhibits a ultra-fast response towards 1 equiv of HOCl (reached a plateau within 2 min) , and it shows a >20-fold increase in fluorescence intensity over other analytes (1 equiv of •OH and ONOO− as well as 10 equiv of O2, NO, 1O2, ROO•, TBHP and H2O2). HKOCl-4 is first tested and it was proven to be non-toxic in living cells even at a concentration up to 50 µM in RAW264.7 macrophages. |