CS-2092
RSV604(RSV604)
CAS: 676128-63-5
化学式: C22H17FN4O2
| 中文名 | RSV604 |
| 英文名 | RSV604 |
| 别名 | 化合物RSV604 |
| 英文别名 | RSV604 CS-2092 RSV 604 Urea, N-[(3S)-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(2-fluorophenyl)- (S)-1-(2-fluoro-phenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea |
| CAS | 676128-63-5 |
| 化学式 | C22H17FN4O2 |
| 分子量 | 388.39 |
| 溶解度 | DMSO: ≥ 195 mg/mL |
| 存储条件 | -20℃ |
| 体外研究 | RSV604 (5 days) inhibits the growth of four laboratory strains of RSV (RSS, Long, A2 and B), with EC 50 s ranging from 0.5 to 0.9 μM in plaque reduction assay. RSV604 (6 days) inhibits RSV-induced HEp-2 cell death, with an EC 50 of 0.86 μM. RSV604 (3 days) reduces viral antigen synthesis in RSV-infected HEp-2 cells, with an EC 50 of 1.7 μM. RSV604 (1-20 μM; 7 days) dose-dependently inhibits RSV infection in human airway epithelial (HAE) cells, with no gross cytotoxicity, leakage of basolateral fluid to the apical surface, or alteration of cilium beat frequency. |
CS-2092 - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.575 ml | 12.874 ml | 25.747 ml |
| 5 mM | 0.515 ml | 2.575 ml | 5.149 ml |
| 10 mM | 0.257 ml | 1.287 ml | 2.575 ml |
| 5 mM | 0.051 ml | 0.257 ml | 0.515 ml |
最后更新：2024-01-02 23:10:35
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