CLOPAMIDE
氯帕胺(clopamide)
CAS: 636-54-4
化学式: C14H20ClN3O3S
| 中文名 | 氯帕胺 |
| 英文名 | clopamide |
| 别名 | 氯丙胺 氯帕胺 克罗帕米 氯哌酰胺 氯帕胺杂质 氯帕胺 EP标准品 氯帕胺系统适用性 EP标准品 4-氯-N-(顺式-2,6-二甲基哌啶基)-3-氨基磺酰基苯甲酰胺 |
| 英文别名 | Aquex Adurix DT-327 CLOPAMIDE clopamide Brinaldix 4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide 4-CHLORO-N-[2,6-DIMETHYLPIPERIDINYL]-3-SULFAMOYLBENZAMIDE 4-chloro-N-(2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide 4-Chloro-N-[(2R,6S)-2,6-dimethylpiperidino)-3-sulfamoylbenzamide 4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide |
| CAS | 636-54-4 |
| EINECS | 211-261-7 |
| 化学式 | C14H20ClN3O3S |
| 分子量 | 345.84 |
| InChI | InChI=1/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+ |
| 密度 | 1.39±0.1 g/cm3(Predicted) |
| 熔点 | 248-249℃ |
| 溶解度 | 氯仿 (轻微、加热、超声处理) 、甲醇 (轻微) |
| 折射率 | 1.613 |
| 酸度系数 | 9.41±0.60(Predicted) |
| 存储条件 | 2-8°C |
| 外观 | 整洁 |
| 颜色 | Pale Yellow to Light Yellow |
| 体外研究 | Clopamide is actively secreted by renal tubular cells and the True Tubular Excretion Fraction (TTEF) value is 10%. |
| 体内研究 | The venoconstrictor response to bradykinin is attenuated after oral administration of Clopamide (0.5 mg/kg), and by concomitant local infusion of cyclosporine-A (1-10 μg/min) in conscious dogs. |
| 危险品标志 | Xn - 有害物品 |
| 风险术语 | 42/43 - 吸入及皮肤接触可能致敏。 |
| 安全术语 | 36 - 穿戴适当的防护服。 |
| WGK Germany | 3 |
| RTECS | CV2338875 |
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