AllerMist
糠酸氟替卡松(FLUTICASONE FUROATE)
CAS: 397864-44-7
化学式: C27H29F3O6S
| 中文名 | 糠酸氟替卡松 |
| 英文名 | FLUTICASONE FUROATE |
| 别名 | 糠酸氟替卡松 氟替卡松糠酸酯 糠酸氟替卡松-[D3] 5-二甲氧基-4-羟基甲苯 |
| 英文别名 | AvaMys Veramyst AllerMist Gw 685698x Unii-js86977wnv (6α,11β,16α,17α)-6,9-Difluoro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-Methyl-3-oxoandrosta-1,4-diene-17-carbothioic Acid S-(FluoroMethyl) Ester Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-17-((2- furanylcarbonyl)oxy)-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6alpha,11beta,16alpha,17alpha)- |
| CAS | 397864-44-7 |
| EINECS | 222-789-2 |
| 化学式 | C27H29F3O6S |
| 分子量 | 538.58 |
| 密度 | 1.39 |
| 熔点 | 250-252°C (dec.) |
| 沸点 | 625.2±55.0 °C(Predicted) |
| 溶解度 | 氯仿 (轻微、加热、超声处理) 、甲醇 (轻微) |
| 酸度系数 | 12.52±0.70(Predicted) |
| 存储条件 | -20°C Freezer |
| 外观 | 固体 |
| 颜色 | White to Off-White |
| 体外研究 | Fluticasone furoate comes in a nasal spray, as an aqueous suspension of micronized fluticasone furoate for topical administration to the nasal mucosa by means of a metering, atomizing spray pump. Fluticasone furonate displays great potency in inhibiting tumor necrosis factor synthesis and action. Fluticasone furonate is also potent in preventing damage to cultured human lung epithelial cells by different stimulus. |
| 体内研究 | Fluticasone furonate is 99.4% bound to plasma protein in vitro and other research indicated extensive first-pass metabolism of the absorbed drug. Protein binding is highly relevant because only the unbound free drug can exert an effect at the receptor site. Clearance of Fluticasone furonate is primarily by hydrolysis in the liver by the cytochrome P450 isozyme (CYP) 3A4 that converts the drug to the 17β-carboxylic acid metabolite (M10), which displays low glucocorticoid receptor agonist potency. Fluticasone furonate is excreted mainly in the feces, with only minor amounts in the urine. |
供应商列表
提供多种规格现货供应
产品名: Fluticasone furoate 去供应商网站查看 询盘CAS: 397864-44-7
产地: 美国
包装: 10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg;200 mg;500 mg
规格: HY-15234
库存: 现货，货期：1-2天
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: 99.84%
现货供应
产品名: 氟替卡松杂质31(糠酸氟替卡松) 去供应商网站查看 询盘CAS: 397864-44-7
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
手机: 15671228036
电子邮件:
产品描述: 458231F
提供多种规格现货供应
产品名: Fluticasone furoate 去供应商网站查看 询盘CAS: 397864-44-7
产地: 美国
包装: 10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg;200 mg;500 mg
规格: HY-15234
库存: 现货，货期：1-2天
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: 99.84%
现货供应
产品名: 氟替卡松杂质31(糠酸氟替卡松) 去供应商网站查看 询盘CAS: 397864-44-7
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
手机: 15671228036
电子邮件:
产品描述: 458231F
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