中文名 | ROCK inhibitor-2 |
英文名 | ROCK inhibitor-2 |
别名 | 化合物ROCK INHIBITOR-2 |
英文别名 | ROCK inhibitor-2 Benzamide, N-[(1R)-1-(3-methoxyphenyl)ethyl]-4-(4-pyridinyl)- |
CAS | 1127308-52-4 |
化学式 | C21H20N2O2 |
分子量 | 332.4 |
密度 | 1.145±0.06 g/cm3(Predicted) |
沸点 | 541.9±50.0 °C(Predicted) |
酸度系数 | 13.41±0.46(Predicted) |
存储条件 | -20℃ |
产品用途 | ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively). |
靶点 | ROCK1; ROCK2; |
参考资料 展开查看 | 1. Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.008 ml | 15.042 ml | 30.084 ml |
5 mM | 0.602 ml | 3.008 ml | 6.017 ml |
10 mM | 0.301 ml | 1.504 ml | 3.008 ml |
5 mM | 0.06 ml | 0.301 ml | 0.602 ml |