中文名 | Magainin I |
英文名 | Magainin I |
别名 | 马加宁I 马盖宁 I 蛙皮素 1 MAGAININ I肽 |
英文别名 | MAGAININ I MAGAININ 1 Magainin I Magainina 1 Magainin I peptide GIGKFLHSAGKFGKAFVGEIMKS Magainin 1 peptide, Xenopus Magainin 1 (Xenopus petersii) GLY-ILE-GLY-LYS-PHE-LEU-HIS-SER-ALA-GLY-LYS-PHE-GLY-LYS-ALA-PHE-VAL-GLY-GLU-ILE-MET-LYS-SER |
CAS | 108433-99-4 |
化学式 | C112H177N29O28S |
分子量 | 2409.85 |
密度 | 1.268±0.06 g/cm3(Predicted) |
沸点 | 2396.1±65.0 °C(Predicted) |
存储条件 | −20°C |
MDL号 | MFCD00133521 |
体外研究 | Magainin 1 interacts with acidic lipids through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8×10 5 M-1 and a binding-site number of 0.10 per lipid molecule. |
WGK Germany | 3 |
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