中文名 | 1-甲基黄嘌呤 |
英文名 | 1-Methylxanthine |
别名 | 甲基黄嘌呤 1-甲基黄嘌呤 1-甲基化黄嘌呤衍生物 6-二羟基-1-甲基嘌呤 2,6-二羟基-1-甲基嘌呤 聽1-METHYLXANTHINE 3,7-二氢-1-甲基-1H-嘌呤-2,6-二酮 |
英文别名 | CCRIS 5816 METHYLXANTHINES 1-methyl-xanthin 1-Methylxanthine 1-METHYLXANTHINE Xanthine, 1-methyl- 2,6-DIHYDROXY-1-METHYLPURINE 3,7-dihydro-1-methyl-1H-purine-2,6-dione 1-Methyl-3,7-dihydro-1H-purine-2,6-dione 1-methyl-3,7-dihydro-1H-purine-2,6-dione 3,7-Dihydro-1-methyl-1H-purine-2,6-dione 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl- |
CAS | 6136-37-4 |
EINECS | 228-108-5 |
化学式 | C6H6N4O2 |
分子量 | 166.14 |
InChI | InChI=1/C6H6N4O2/c1-10-5(11)3-4(8-2-7-3)9-6(10)12/h2H,1H3,(H,7,8)(H,9,12) |
InChIKey | MVOYJPOZRLFTCP-UHFFFAOYSA-N |
密度 | 1.539±0.06 g/cm3(Predicted) |
熔点 | ≥300°C |
溶解度 | 水基 (微溶),DMSO (微溶) |
折射率 | 1.626 |
酸度系数 | pK1:7.70;pK2:12.0 (25°C) |
存储条件 | Sealed in dry,Room Temperature |
外观 | 固体 |
颜色 | Pale Yellow to Dark Yellow |
最大波长(λmax) | ['270nm(H2O)(lit.)'] |
BRN | 171507 |
MDL号 | MFCD00005561 |
体外研究 | 1-Methylxanthine (1-MTX; 3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death. 1-Methylxanthine (1MX) exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine, TP, and theobromine, 3-Methylxanthine (3MX) and 1-methylxanthine do not occur naturally at high levels in plants. |
危险品标志 | T+ - 极高毒性物品 |
风险术语 | 26/27/28 - 吸入、皮肤接触及吞食有极高毒性。 |
安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 3 |
RTECS | ZD8575000 |
海关编号 | 29335990 |
上游原料 | 醋酸 钠 N,N-二甲基甲酰胺 对甲苯磺酸 氰乙酸乙酯 三水合醋酸钠 |
参考资料 展开查看 | 1. [IF=4.072] Meng-zhen Zhou et al."Discovery and Biochemical Characterization of N-methyltransferase Genes Involved in Purine Alkaloid Biosynthetic Pathway of Camellia gymnogyna Hung T.Chang (Theaceae) from Dayao Mountain."Phytochemistry. 2022 Jul;199:113167 |