中文名 | 地芬尼泰 |
英文名 | diamfenetide |
别名 | 地芬尼太 双胺酚醚 地芬尼泰 Β,Β'-双(4-乙酰胺基苯氧基)乙醚 N-[4-[2-[2-(4-乙酰氨基苯氧基)乙氧基]乙氧基]苯基]乙酰胺 |
英文别名 | Coriban coryphamin acemidophene diamfenetide .beta.,.beta.'-Oxybis[p-acetophenetidide] n,n'-(oxybis(2,1-ethanediyloxy-4,1-phenylene))bisacetamide n,n'-(oxybis(2,1-ethanediyloxy-4,1-phenylene))bis-acetamid N,N'-[Oxybis(2,1-ethanediy-loxy-4,1-phenylene)]bisacetamide Acetamide, N,N'-[oxybis(2,1-ethanediyloxy-4,1-phenylene)]bis- |
CAS | 36141-82-9 |
EINECS | 252-886-5 |
化学式 | C20H24N2O5 |
分子量 | 372.42 |
物化性质 | 白色或浅黄色结晶性粉末。熔点142℃。微溶于乙醇,不溶于水。 |
体外研究 | Diamfenetide (10-100μM; 1-3 hours) treatment leads a time/dose-dependent, irreversible paralysis that involves an increase in muscular tension and decrease in contraction amplitude in vitro of immature and adult Fasciola hepatica.Diamfenetide (100μM; 6-24 hours) increases products of glucose metabolism by adult Fasciola hepatica in vitro. And the metabolic effects of Diamfenetide on F. hepatica may be secondary to the initial effects on surface membranes. |
上游原料 | 二乙二醇 扑热息痛 二氯乙醚 |