β-Naphthoflavon
Beta-Naphthoflavone
CAS: 6051-87-2
Molecular Formula: C19H12O2
β-Naphthoflavon - Names and Identifiers
| Name | Beta-Naphthoflavone |
| Synonyms | β-Naphthoflavon 5,6-BENZOFLAVONE 5,6-Benzoflavone β-Naphthoflavone Beta-Naphthoflavone 3-Phenyl-benzo[f]chromen-1-one 3-phenyl-1H-benzo[f]chromen-1-one 3-Phenyl-1H-benzo[f]chromen-1-one 3-Phenyl-1H-naphtho(2,1-b)pyran-1-one 3-Phenyl-1H-naphtho[2,1-b]pyran-1-one 1H-Naphtho[2,1-b]pyran-1-one,3-phenyl- |
| CAS | 6051-87-2 |
| EINECS | 227-958-4 |
| InChI | InChI=1/C19H12O2/c20-16-12-18(14-7-2-1-3-8-14)21-17-11-10-13-6-4-5-9-15(13)19(16)17/h1-12H |
β-Naphthoflavon - Physico-chemical Properties
| Molecular Formula | C19H12O2 |
| Molar Mass | 272.3 |
| Density | 1.1382 (rough estimate) |
| Melting Point | 164-166 °C (lit.) |
| Boling Point | 275-280 °C (1 mmHg) |
| Flash Point | 215.8°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| Vapor Presure | 1.12E-08mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | yellow to tan |
| BRN | 18991 |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5510 (estimate) |
| MDL | MFCD00004986 |
β-Naphthoflavon - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R34 - Causes burns R11 - Highly Flammable |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S16 - Keep away from sources of ignition. |
| WGK Germany | 3 |
| RTECS | QL6200000 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29329900 |
| Hazard Note | Irritant |
β-Naphthoflavon - Reference
| Reference Show more | 1. Wang Chengyu, Li Dengke, Quan Zhengyang, Hu Ying also, Sun Zhenxiao. Study on hepatotoxicity and related components of Polygonum multiflorum based on cytochrome oxidase CYP2D6 [J]. Pharmacovigilance in China, 2021,18(03):220-227 239. |
β-Naphthoflavon - Introduction
Beta-Naphthoflavone(Beta-Naphthoflavone) is an organic compound with the structure of flavonoids. Its chemical formula is C20H12O2 and its molecular weight is 284.31.
Beta-Naphthoflavone have some of the following main properties:
1. appearance: the Beta-Naphthoflavone is light yellow crystal or powder substance.
2. melting point: its melting point is between 161-166 ℃.
3. Solubility: Beta-Naphthoflavone is soluble in alcohol, ethanol, chloroform and dimethyl sulfoxide, but less soluble in water.
Beta-Naphthoflavone is mainly used in the following aspects:
1. enzyme inducer: Beta-Naphthoflavone is an effective enzyme inducer, which can activate the activity of some drug metabolism enzymes and affect the metabolism and clearance rate of drugs.
2. Research use: Due to its induction of cytochrome P450 enzymes, it can be used as a substrate or reagent in drug metabolism research.
3. Toxicity research: Beta-Naphthoflavone can be used as a model for toxic and carcinogenic substances in experimental research for toxicity and carcinogenicity research.
The preparation of Beta-Naphthoflavone can be obtained by various means. One of the common methods is the reaction of ethyl iodoacetate and β-naphthol under alkaline conditions to form Beta-Naphthoflavone.
When using and handling Beta-Naphthoflavone, you need to pay attention to safety matters. Here are some common security messages:
1. Beta-Naphthoflavone flammable at high temperature and fire, should be stored in a cool and dry place.
2. it is recommended to wear protective gloves, glasses and protective clothing and other personal protective equipment.
3. avoid inhaling its dust or solution, avoid contact with skin and eyes.
4. After contact, rinse immediately with plenty of water and seek medical treatment.
It should be noted that Beta-Naphthoflavone is a chemical reagent with certain toxicity and danger. It should be operated in accordance with relevant laboratory and safety regulations when used.
Beta-Naphthoflavone have some of the following main properties:
1. appearance: the Beta-Naphthoflavone is light yellow crystal or powder substance.
2. melting point: its melting point is between 161-166 ℃.
3. Solubility: Beta-Naphthoflavone is soluble in alcohol, ethanol, chloroform and dimethyl sulfoxide, but less soluble in water.
Beta-Naphthoflavone is mainly used in the following aspects:
1. enzyme inducer: Beta-Naphthoflavone is an effective enzyme inducer, which can activate the activity of some drug metabolism enzymes and affect the metabolism and clearance rate of drugs.
2. Research use: Due to its induction of cytochrome P450 enzymes, it can be used as a substrate or reagent in drug metabolism research.
3. Toxicity research: Beta-Naphthoflavone can be used as a model for toxic and carcinogenic substances in experimental research for toxicity and carcinogenicity research.
The preparation of Beta-Naphthoflavone can be obtained by various means. One of the common methods is the reaction of ethyl iodoacetate and β-naphthol under alkaline conditions to form Beta-Naphthoflavone.
When using and handling Beta-Naphthoflavone, you need to pay attention to safety matters. Here are some common security messages:
1. Beta-Naphthoflavone flammable at high temperature and fire, should be stored in a cool and dry place.
2. it is recommended to wear protective gloves, glasses and protective clothing and other personal protective equipment.
3. avoid inhaling its dust or solution, avoid contact with skin and eyes.
4. After contact, rinse immediately with plenty of water and seek medical treatment.
It should be noted that Beta-Naphthoflavone is a chemical reagent with certain toxicity and danger. It should be operated in accordance with relevant laboratory and safety regulations when used.
Last Update：2024-04-10 22:43:14
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