pentachlorophenol
pentachlorophenol - Names and Identifiers
| Name | Pentachlorophenol |
| Synonyms | Acutox angeldust Pentachlorophenol Gasoline,air fuel Pentachlorophenol tech 2,3,4,5,6-Pentachlorophenol 1-Hydroxypentachlorobenzene PentachloropentadienoicAcid 1-(1-phenylcyclohexyl)-piperidin 1-Hydroxy-2,3,4,5,6-pentachlorobenzene |
| CAS | 87-86-5 |
| EINECS | 201-778-6 |
| InChI | InChI=1/C6HCl5O/c7-1-2(8)4(10)6(12)5(11)3(1)9/h12H |
pentachlorophenol - Physico-chemical Properties
| Molecular Formula | C6HCl5O |
| Molar Mass | 266.34 |
| Density | 1.978g/mLat 25°C(lit.) |
| Melting Point | 165-180°C(lit.) |
| Boling Point | 310°C(lit.) |
| Flash Point | 11°C |
| Water Solubility | 80 mg l-1(30 °C) |
| Vapor Presure | 40 mm Hg ( 211.2 °C) |
| Vapor Density | 9.2 (vs air) |
| Appearance | Liquid |
| Specific Gravity | 1.979 |
| Exposure Limit | NIOSH REL: IDLH 0.5 mg/m3, IDLH 2.5 mg/m3; OSHA PEL: TWA0.5 mg/m3; ACGIH TLV: TWA 0.5 mg/m3 |
| Merck | 7109 |
| BRN | 1285380 |
| pKa | 4.80 (Blackman et al., 1955)5.3 (Eder and Weber, 1980) |
| Storage Condition | 0-6°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.6310 (estimate) |
| Physical and Chemical Properties | Pure white crystals. Melting Point: 174 ℃ with 1 crystal water; Anhydrous matter 191 ℃, boiling point 309-310 ℃(100.525kPa, decomposition), relative density 1.978(22/4 ℃). Soluble in dilute alkali and acetone, ethanol, ethyl ether, benzene and other organic solvents, micro-soluble in water. |
| Use | Used as standard substance for pesticide analysis |
pentachlorophenol - Nature
Open Data Verified Data
white or yellowish needle-like crystals with special odor. Soluble in water, solubility in water for 26. 1%. Soluble in ethanol, methanol, acetone, micro-soluble carbon tetrachloride and carbon disulfide, insoluble in petroleum and benzene, alkaline aqueous solution, acid acidification to pH 6.8~6.6, all precipitation of pentachlorophenol. Non-volatile at room temperature. Rapid decomposition under light, the removal of hydrogen chloride, the color change is easy to decompose when the sun is irradiated, the nature of the dry is stable, the decomposition of the high heat, the emission of corrosive, irritating smoke.
Last Update：2025-06-10 22:55:16
pentachlorophenol - Preparation Method
Open Data Verified Data
by trichlorobenzene chloride, hexachlorobenzene, hexachlorobenzene and a certain concentration of caustic soda solution heating, hydrolysis at a certain temperature and pressure, the reaction product after cooling, crystallization, sodium pentachlorophenol was obtained by filtration and drying.
Last Update：2025-06-10 22:55:16
pentachlorophenol - Application
Open Data Verified Data
bactericide, combined with some anionic surface activity, can significantly reduce its dosage and improve the bactericidal effect. But it is not suitable for use with cationic agents (such as quaternary ammonium salts, etc.). Pentachlorophenol sodium use mass concentration is generally 50mg/L.
Last Update：2025-08-19 16:24:40
pentachlorophenol - Safety
Open Data Verified Data
rat oral LD50:140 ~ 280mg/kg, rat percutaneous 66mg/kg, rat inhalation LC50 L52 mg/m3, Mouse Inhalation 229mg/m3. Human Oral minimum lethal dose 30mg/kg, human percutaneous minimum lethal dose 60mg/kg. It has strong toxicity to fish, and the lethal concentration of LDso is 0.3~0. 6mg/L. The maximum allowable concentration of harmful substances in the air of workshops in China is 0. 3mg/m3. This product is irritating to the eyes and respiratory tract. Acute poisoning is mainly caused by skin contact or drinking contaminated water. Staff should be protected. If the skin and eyes are touched, they should immediately rinse thoroughly with plenty of flowing water. Store in a cool, ventilated warehouse. Keep away from fire and heat source. Protected from light. Keep the container sealed. It should be stored separately from oxidants, acids and edible chemicals, and mixed storage should not be avoided.
Last Update：2022-01-01 09:29:23
pentachlorophenol - Reference Information
| Henry's Law Constant | 21 (quoted, Petrasek et al., 1983) |
| (IARC) carcinogen classification | 1 (Vol. 53, 71, 117) 2019 |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Overview | pentachlorophenol (PCP) is white flake or crystalline solid in appearance, usually containing one molecule of crystal water, it is slightly hot and has a strong spicy smell. When it is dissolved in water, it generates corrosive hydrochloric acid gas; Industrial products are gray-black powder or flaky solid, melting point 187~189 ℃, boiling point about 309-310 ℃ (decomposition). Insoluble in water, solubility (20 ℃)20~25mg/L, soluble in most organic solvents such as ethanol, ether, benzene, slightly soluble in cold petroleum ether, but the solubility in carbon tetrachloride and paraffin is not large. It is acidic and has no corrosive effect on most metals in the absence of moisture. It reacts with sodium hydroxide to form white sodium salt crystals soluble in water. Incompatible with strong oxidants. Good stability, no ignition in air at 550 ℃. It is produced industrially from the direct chlorination of phenol in the presence of a catalyst or from hexachlorocytoses (α,β-isomers). Pentachlorophenol (PCP) is an important preservative, it can prevent the growth of fungi, inhibit bacterial corrosion, has long been used as leather and wood fungicides, it is effective for the control of mold and general insects (such as termites), and its sodium salt is used to eliminate the intermediate host of schistosomiasis, Oncomelania hupensis, and control the grass. Sensitive to fish and other aquatic animals, water content of 0.1-0.5ppm is lethal. Organic drugs, can be absorbed through the skin, the liver, kidney damage. Ingestion can lead to poisoning and death in severe cases. However, in the past decade, medical research has found that if you often contact with products containing pentachlorophenol (PCP), it is very likely to affect human health, and the symptoms include Head Pain, Abdominal Pain, vomit and the central nervous system damage. The German government has established legislation to limit the content of pentachlorophenol (PCP) to 5ppm, which applies to a variety of products that have been treated with PCP and PCP compounds, such as bags and wristbands. All products exported to the German market must pass the above tests. China's ecological textile standards and the international ecological textile association of the oeko-tex standard 100 of the PCP residues in textiles should not exceed 0.5mg/kg (infant products should not exceed 0.05mg/kg) limit. |
| Use | is used in organic synthesis, control of rice fields, and wood preservation. Is also widely used fungicide, sterilization effect is high, suitable for polyvinyl chloride and other plastics, coatings, leather, adhesives, rubber, fiber, paper, etc., the general dosage of 0.1-0.5%. It is also effective for the control of termites, snails and the like. use as jet engine fuel use as reference material for pesticide analysis |
| production method | sodium pentachlorophenol is prepared by high-pressure hydrolysis using hexaenoic acid as raw material and then acidified. |
| category | pesticide |
| toxicity grade | highly toxic |
| Acute toxicity | oral-rat LD50: 27 mg/kg; Oral-mouse LD50: 36 mg/kg |
| stimulation data | Skin-moderate in rabbits at 10 mg/24 h; eye-rabbit 0.1/24 h mild |
| flammability hazard characteristics | non-combustible; Thermal decomposition of toxic chloride gases |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
| fire extinguishing agent | Sand, dry powder, foam |
| Occupational Standard | TWA 0.5 mg/m3; Tel 1.5 mg/m3 |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
| immediate life-threatening and health concentration | 2.5 mg/m3 |
Last Update：2024-04-09 02:00:12
