mal-PEG-NHS

mal-PEG-NHS - Names and Identifiers

Name	NHS-PEG-MAL
Synonyms	mal-PEG-NHS NHS-PEG-MAL NHS-PEG2K-MAL NHS-PEG5K-MAL NHS-PEG3.4K-MAL alpha-Maleinimido-omega-carboxy succinimidyl ester poly(ethylene glycol) (PEG-MW 5.000 Dalton) alpha-Maleinimido-omega-carboxy succinimidyl ester poly(ethylene glycol) (PEG-MW 3.000 Dalton) alpha-Maleinimido-omega-carboxy succinimidyl ester poly(ethylene glycol) (PEG-MW 10.000 Dalton)

mal-PEG-NHS - Physico-chemical Properties

Molecular Formula	C22H31N3O9
Molar Mass	481.49624
Storage Condition	-20°C

mal-PEG-NHS - Introduction

NHS-PEG-MAL(NHS-PEG-MAL) is a commonly used chemical reagent. It is composed of the active ester compound N-hydroxysuccinimide (NHS) combined with polyethylene glycol (PEG) group and maleimide (MAL) group. Its nature is as follows:

1. active properties: NHS-PEG-MAL has activated affinity groups, which can react rapidly with biological molecules containing functional groups (such as amino groups, sulfhydryl groups, etc.).

2. solubility: NHS-PEG-MAL soluble in water, but also soluble in some organic solvents (such as DMF, DMSO, etc.).

The main uses of NHS-PEG-MAL are as follows:

1. cross-linking reagent: NHS-PEG-MAL can be used to cross-link with proteins, antibodies and other biological macromolecules to prepare polymer composites with improved stability and solubility.

2. Targeted drug delivery: NHS-PEG-MAL can be used to modify drug carriers (such as nanoparticles, microspheres, etc.) to increase their stability and targeting in vivo.

3. Biosensors: NHS-PEG-MAL can be used to prepare biosensors for detecting and analyzing the presence and concentration of biomolecules.

The preparation of NHS-PEG-MAL is generally achieved by chemical synthesis. Specifically, NHS, PEG and MAL are reacted according to a certain molar ratio, and subjected to deionized water treatment and purification steps to prepare NHS-PEG-MAL.

Pay attention to the following safety information when using the NHS-PEG-MAL:

1. Avoid contact with skin and eyes: NHS-PEG-MAL are chemical reagents, direct contact with skin and eyes should be avoided. In case of contact, rinse immediately with plenty of water and seek medical attention.

2. storage note: NHS-PEG-MAL should be stored in a dry, cool, dark place, avoid direct sunlight and high temperature.

3. Pay attention to ventilation during operation: When operating NHS-PEG-MAL, please ensure a well-ventilated working environment to avoid inhaling aerosols or dust.

4. Comply with laboratory specifications: When using NHS-PEG-MAL, you should comply with laboratory operating specifications and related regulations to ensure safety and correct operation.

Last Update：2024-04-09 21:21:28