dacarbazine
dacarbazine
CAS: 4342-03-4
Molecular Formula: C6H10N6O
dacarbazine - Names and Identifiers
dacarbazine - Physico-chemical Properties
| Molecular Formula | C6H10N6O |
| Molar Mass | 182.18 |
| Density | 1.3206 (rough estimate) |
| Melting Point | 199-205°C |
| Boling Point | 315.57°C (rough estimate) |
| Flash Point | 229.734°C |
| Water Solubility | Slightly soluble in water, DMSO and ethanol/n |
| Solubility | Slightly soluble in water and ethanol, slightly soluble in dilute hydrochloric acid |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | A loose lump or powder that is white, yellowish, or slightly reddish. |
| Color | Off-White to Light Yellow |
| Merck | 14,2798 |
| pKa | pKa 4.42 (Uncertain) |
| Storage Condition | 2-8°C |
| Sensitive | Sensitive to heat and light |
| Refractive Index | 1.7500 (estimate) |
| MDL | MFCD00057167 |
| Physical and Chemical Properties | Yellowish crystals or powder. The melting point was 205 °c, and 250-255 °c (decomposition) was also reported. Soluble in acid, slightly soluble in methanol, ethanol, insoluble in water. Thermal decomposition, unstable to acid and light. |
| Use | Anti-tumor drugs, mainly used for melanoma, also used for soft tissue sarcoma and malignant lymphoma |
dacarbazine - Risk and Safety
| Risk Codes | R45 - May cause cancer R46 - May cause heritable genetic damage R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | NI3950000 |
| HS Code | 29349990 |
dacarbazine - Reference
| Reference Show more | 1. [IF=6.529] Gui Chen et al."Microbiome analysis combined with targeted metabolomics reveal immunological anti-tumor activity of icariside I in a melanoma mouse model."Biomed Pharmacother. 2021 Aug;140:111542 |
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View History
dacarbazine
Oxalic acid hydrazide
19752-84-2
Teratop Violet BL
AI3-62312
Sanggenone D
1-Cyclohexylmethanol
3,5-DIMETHYLBENZYL BRROMIDE
3333-67-3
Pigment Red 4 (C.I.)
Oxalic acid hydrazide
19752-84-2
Teratop Violet BL
AI3-62312
Sanggenone D
1-Cyclohexylmethanol
3,5-DIMETHYLBENZYL BRROMIDE
3333-67-3
Pigment Red 4 (C.I.)