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corynoline

corynoline

CAS: 18797-79-0

Molecular Formula: C21H21NO5

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corynoline - Names and Identifiers

Name corynoline
Synonyms corynoline
CORYNOLINE
CORYNOLINE(P)
(+)-corynoline
13-methylchelidonine
dimethyl-, (5bR,6S,12bR)-
13-Methylchelidonan-11β-ol
[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-
(5bR)-5bα,13-Dimethyl-5bα,6,7,12bα,13,14-hexahydro[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-6β-ol
[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol, 5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, (5bR,6S,12bR)-
CAS 18797-79-0
InChI InChI=1/C21H21NO5/c1-21-14-3-4-15-19(27-10-24-15)13(14)8-22(2)20(21)12-7-17-16(25-9-26-17)5-11(12)6-18(21)23/h3-5,7,18,20,23H,6,8-10H2,1-2H3/t18-,20+,21-/m0/s1

corynoline - Physico-chemical Properties

Molecular FormulaC21H21NO5
Molar Mass367.4
Density1.395±0.06 g/cm3(Predicted)
Melting Point180~181℃
Boling Point504.2±50.0 °C(Predicted)
Specific Rotation(α)+132 (c, 2.64 in CHCl3) (+116.4)
Flash Point258.7°C
Solubility DMSO : 41.67 mg/mL (113.42 mM; Need ultrasonic)
Vapor Presure5.48E-11mmHg at 25°C
AppearanceColorless granular crystal
ColorOff-White to Pale Yellow
pKa14.14±0.40(Predicted)
Storage ConditionAmber Vial, -20°C Freezer, Under inert atmosphere
StabilityLight Sensitive
Refractive Index1.659
MDLMFCD11042250
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Kudi Ding.

corynoline - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
HS Code29389090

corynoline - Reference Information

biological activity Corynoline, which can be separated from Corydalis incise (Papaveraceae), is a reversible and non Competitive acetylcholinesterase (AChE) inhibitor, IC50 is 30.6 μM. Corynoline exert anti-inflammatory effect by activating Nrf2.
chemical properties white crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Kudi Ding.
use corydalis has sedative and anti-leptospira effects.
used for content determination/identification/pharmacological experiments and other pharmacological effects: inhibition of acetylcholinesterase
Last Update:2024-04-09 20:49:11
corynoline
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Shanghai Yuanye Bio-Technology Co., Ltd.
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CAS: 18797-79-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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