Name | 2-Chloroacetamide |
Synonyms | KM 101 NSC 8408 mergalaf NSC 54286 Mergal AF microcide mergal af chloracetamid Chloracetamide chloroacetamide 2-chloroacetamid Piracetam Imp. B 2-Chloroacetamide chloroacetylamine 2-chloroethanamide 2-chloro acetamide acetamide,2-chloro- alpha-chloracetamide alpha-chloroacetamide chloracetamid(α-form,stabileform) |
CAS | 79-07-2 |
EINECS | 201-174-2 |
InChI | InChI=1/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5) |
InChIKey | VXIVSQZSERGHQP-UHFFFAOYSA-N |
Molecular Formula | C2H4ClNO |
Molar Mass | 93.51 |
Density | 0.84 |
Melting Point | 116-118°C(lit.) |
Boling Point | 224.5 °C |
Flash Point | 170 °C |
Water Solubility | Soluble in water(90g/L). |
Solubility | Soluble in 10 times water and 10 times absolute ethanol, very slightly soluble in ether. |
Vapor Presure | 0.05 mm Hg ( 20 °C) |
Appearance | White crystal |
Color | White |
Merck | 14,2110 |
BRN | 878191 |
pKa | 14.69±0.40(Predicted) |
PH | 3.8-4.1 (40g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Refractive Index | 1.4480 (estimate) |
MDL | MFCD00008027 |
Physical and Chemical Properties | Character white crystals. |
Use | For the synthesis of chloroacetonitrile, sulfamethoxazole pyrazine and other organic compounds |
Hazard Symbols | T - Toxic |
Risk Codes | R25 - Toxic if swallowed R43 - May cause sensitization by skin contact R62 - Possible risk of impaired fertility |
Safety Description | S22 - Do not breathe dust. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 2 |
RTECS | AB5075000 |
TSCA | Yes |
HS Code | 29241900 |
Hazard Class | 6.1 |
Packing Group | III |
Toxicity | LD50 orally in Rabbit: 138 mg/kg LD50 dermal Rat > 2000 mg/kg |
white crystals. Melting Point 121 °c. Boiling point 225 degrees C (decomposition). Soluble in 10 times the water and 10 times the absolute ethanol. Very slightly soluble in ether.
with ethyl chloroacetate as raw material, Dropwise adding ammonia at less than 10 ℃, white crystals are precipitated, ammonium chloride is washed with ammonia, and the crude 2-chloroacetamide is filtered, and finally recrystallized with ethanol, that's right.
It is used for the synthesis of organic compounds such as chloroacetonitrile and sulfamethazine.