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chlormezanone

chlormezanone

CAS: 80-77-3

Molecular Formula: C11H12ClNO3S

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chlormezanone - Names and Identifiers

Name chlormezanone
Synonyms Lobak
201-307-4
chlormezanone
(±)-Chlormezanone
Dichloromethazanone
ChlorMezanone (Trancopal)
2-(4-Chlorophenyl)-3-methyl-4-thiazanone 1,1-dioxide
2-(4-Chlorophenyl)-3-methyl-4-metathiazanone-1,1-dioxide
2-(4-Chlorophenyl)-3-methyl-4-metathiazanone 1,1-Dioxide
2-(4-chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
2-(p-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one
2-(4-Chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide
2-(p-chlorophenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide
2-(p-Chlorophenyl)perhydro-3-methyl-1,3-thiazin-4-one 1,1-Dioxide
2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide
2-(para-chlorophenyl)tetrahydro-3-methyl-4h-1,3-thiazin-4-one,1,1-dioxide
4H-1,3-Thiazin-4-one, 2-(4-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide
CAS 80-77-3
EINECS 201-307-4
InChI InChI=1/C11H12ClNO3S/c1-13-10(14)6-7-17(15,16)11(13)8-2-4-9(12)5-3-8/h2-5,11H,6-7H2,1H3

chlormezanone - Physico-chemical Properties

Molecular FormulaC11H12ClNO3S
Molar Mass273.74
Density1.2205 (rough estimate)
Melting Point114 °C
Boling Point534.5±50.0 °C(Predicted)
Flash Point277.1°C
Solubility DMSO 55 mg/mL;Water <1 mg/mL;Ethanol 26 mg/mL. Slightly soluble in water or ethanol, easily soluble in acetone, chloroform, insoluble in benzene.
Vapor Presure1.68E-11mmHg at 25°C
AppearanceWhite crystalline powder
ColorWhite to Pale Yellow
Merck14,2106
pKa-2.37±0.40(Predicted)
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.6300 (estimate)
MDLMFCD00143951
Physical and Chemical PropertiesWhite crystalline powder. Melting point 116.2-118.2 °c. Slightly soluble in water or ethanol, soluble in acetone, chloroform, insoluble in benzene. Slightly odorous. Decomposition upon heating in an inorganic acid or base.
UseWeak tranquilizer, used for nervous tension fear, chronic fatigue, Anxiety, excitement and irritability caused by certain diseases such as insomnia
In vivo study Comparative results obtained with Chlormezanone in the dosage levels capable of producing more than 80% depression in the contralateral extensor.

chlormezanone - Risk and Safety

RTECSXJ1050000

chlormezanone - Reference Information

NIST chemical information information provided by: webbook.nist.gov (external link)
biological activity Chlormezanone is a non-benzodiazepine for the treatment of anxiety disorders. It has been suggested for the treatment of muscle spasms.
Target Benzodiazepine
Use is used as a weak neuroleptic. With sedation, stability and central muscle relaxation effect. Can also be used for nervous fear, chronic fatigue, Anxiety, excitement, and certain diseases caused by irritability and insomnia. Because of muscle relaxation, with analgesics can be used for back acid, hard neck, bone pain, spine and limbs pain and rheumatism Arthralgia.
A weak neuroleptic, used for nervousness, fear, chronic fatigue, Anxiety, agitation and irritability caused by certain diseases such as insomnia
production method from p-chlorobenzaldehyde by condensation with methylamine solution, mercaptopropionic acid cyclization, potassium permanganate solution oxidation.
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update:2024-04-09 21:54:55
chlormezanone
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 80-77-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Chlormezanone Request for quotation
CAS: 80-77-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-Dioxide Visit Supplier Webpage Request for quotation
CAS: 80-77-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
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Product Name: Chlormezanone Visit Supplier Webpage Request for quotation
CAS: 80-77-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-Dioxide Visit Supplier Webpage Request for quotation
CAS: 80-77-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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