c3225
dibucaine hydrochloride
CAS: 61-12-1
Molecular Formula: C20H30ClN3O2
c3225 - Names and Identifiers
| Name | dibucaine hydrochloride |
| Synonyms | c3225 Dibucaine HCL Cinchocaine HCl dibucaine hydrochloride cinchocaine hydrochloride benzolin(localanesthetic) Dibucaine (Cinchocaine) HCl butoxycinchoninicaciddiethylethylenediamidehydrochloride 2-n-butoxy-n-(2-diethylaminoethyl)cinchoninamidehydrochloride 2-butoxy-n-(2-(diethylamino)ethyl)-cinchoninamidmonohydrochloride 2-butoxy-n-(2-diethylaminoethyl)cinchoninicacidamidehydrochloride 2-butoxy-n-(2-(diethylamino)ethyl)-4-quinolinecarboxamidmonohydrochlorid 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide dihydrochloride 2-{[(2-butoxyquinolin-4-yl)carbonyl]amino}-N,N-diethylethanaminium chloride 4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-,monohydrochloride |
| CAS | 61-12-1 |
| EINECS | 200-498-1 |
| InChI | InChI=1/C20H29N3O2.2ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);2*1H |
c3225 - Physico-chemical Properties
| Molecular Formula | C20H30ClN3O2 |
| Molar Mass | 379.92 |
| Density | 1.1338 (rough estimate) |
| Melting Point | 99-101°C(lit.) |
| Boling Point | 544.7°C at 760 mmHg |
| Flash Point | 283.2°C |
| Water Solubility | Freely soluble in water, alcohol, acetone, or chloroform |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 3.37E-12mmHg at 25°C |
| Appearance | Solid |
| Color | Hygroscopic crystals |
| Merck | 13,3057 |
| PH | pH(20g/l,25℃) : 5.0～6.0 |
| Storage Condition | Refrigerator |
| Stability | Stable. Incompatible with strong oxidizing agents. Protect from moisture. |
| Refractive Index | 1.5400 (estimate) |
| Physical and Chemical Properties | Melting point 99-101°C |
| Use | Used as a local anesthetic |
| In vitro study | Dibucaine (Cinchocaine) HCl is one of the most effective and toxic local anesthetics. Dibucaine (Cinchocaine) HCl blocks the generation and conduction of nerve impulses by reducing the permeability of neuronal cell membranes to sodium ions. This reversibly stabilizes the cell membrane and inhibits depolarization, leading to conduction failure of the action potential and subsequent conduction block. |
c3225 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| RTECS | GD3325000 |
| HS Code | 2933492250 |
| Toxicity | eye-rbt 2% SEV ARZNAD 8,181,58 |
c3225 - Reference Information
| biological activity | Dibucaine HCl (Cinchocaine) is a local anesthetic. |
| Target | Value |
| use | this product is an amide anesthetic. among the local anesthetics used in clinical application, ocicaine is the one with the strongest effect, the greatest toxicity and the longest maintenance time. The anesthetic intensity of injection administration is 15 times that of procaine, and the toxicity is 15 times greater. The onset is slow, about 15min, but the duration of action is 3 times that of procaine. Local irritation is small and penetration is strong. Used for topical anesthesia, infiltration anesthesia or epidural anesthesia. Used as a local anesthetic |
| Production method | 2-hydroxyquinoline carboxylic acid is chlorinated, condensed, butyl etherified, and salted to obtain ocicaine. |
Last Update：2024-04-09 21:04:16
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Multiple SpecificationsSpot supply
Product Name: Dibucaine hydrochloride Request for quotationCAS: 61-12-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Dibucaine hydrochloride Visit Supplier Webpage Request for quotationCAS: 61-12-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Cinchocaine hydrochloride Visit Supplier Webpage Request for quotationCAS: 61-12-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
View History
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