XYLOMETAZOLINE
2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE
CAS: 526-36-3
Molecular Formula: C16H24N2
XYLOMETAZOLINE - Names and Identifiers
XYLOMETAZOLINE - Physico-chemical Properties
| Molecular Formula | C16H24N2 |
| Molar Mass | 244.38 |
| Density | 1.00±0.1 g/cm3(Predicted) |
| Melting Point | 131-133° |
| Boling Point | 394.2±21.0 °C(Predicted) |
| pKa | pKa 10.6±0.1(H2Ot = 22.0) (Uncertain) |
XYLOMETAZOLINE - Risk and Safety
| Toxicity | LD50 oral in mouse: 215mg/kg |
XYLOMETAZOLINE - References
| Application | ciloxazoline is an effective local nasal vasoconstrictor that acts directly on the nasal mucosa α-adrenergic receptors, produce vasoconstrictive effect, thereby reducing blood flow and nasal congestion, with rapid, rapid ventilation, lasting, side effects, the possibility of causing reactive hyperemia is very small, and the characteristics of selloazoline to reduce inflammation caused by congestion and edema, clinical to reduce acute and chronic rhinitis, sinusitis, allergic rhinitis, hypertrophic rhinitis and other diseases caused by Nasal Congestion symptoms, with rapid onset, lasting effect, side effects and other characteristics. |
| Use | xyloazoline has the effect of inducing vasoconstriction by directly activating α1 receptor, so as to reduce inflammation caused by congestion and edema, clinical to reduce acute and chronic rhinitis, sinusitis, allergic rhinitis, hypertrophic rhinitis and other diseases caused by Nasal Congestion symptoms. |
| biological activity | xylomethazoline (Ba-11391, Otrivine, Rhinoxilin) is a nasal vasoconstrictor hyperemic agent, can be used to improve Nasal Congestion, allergic rhinitis and sinusitis symptoms. |
Last Update：2024-04-10 22:29:15
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