Molecular Formula | C43H52N4O5 |
Molar Mass | 704.9 |
Density | 1.30±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 223℃ (dec.) (methanol ) |
Specific Rotation(α) | D20 -52° (chloroform) |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | White crystalline powder |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. |
Reference Show more | Bai Ya-Zhu, Zheng Zhi-Zhong, Chen Qing-Zhi, et al. In vitro antitumor effects of four indole alkaloids from African horseshoe fruit [J]. Subtropical plant science, 2019, 29 (3). |
introduction | old chestnut amine is an alkaloid in the bark of fukang tree, which can be separated from the ethyl acetate percolation extract of fukang tree. Old spinylamine has antimalarial activity in vivo, and also has in vitro activity to kill the preflagellates of Leishmania infants. |
biological activity | Voacamine is an indole alkaloid isolated from Voacanga Africana. Voacamine has potent cannabinoid CB1 receptor antagonistic activity. Voacamine also inhibits the effect of P-glycoprotein (P-gp) in multidrug resistant tumor cells. |
chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. |
use | used for content determination/identification/pharmacological experiments, etc. |