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VX-661

VX-661

CAS: 1152311-62-0

Molecular Formula: C26H27F3N2O6

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VX-661 - Names and Identifiers

Name VX-661
Synonyms VX661
VX 661
VX-661
TEZACAFTOR
1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methyl-2-propanyl)-1H-indol-5-yl}cyclopropanecarboxamide
Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-
(R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-Methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxaMide
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide VX661
CAS 1152311-62-0
InChI InChI=1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1

VX-661 - Physico-chemical Properties

Molecular FormulaC26H27F3N2O6
Molar Mass520.5
Density1.49±0.1 g/cm3(Predicted)
Boling Point610.8±55.0 °C(Predicted)
pKa13.99±0.20(Predicted)
Storage Condition-20℃
In vitro studyVX-661 is a CFTR correction drug that protects the F508del mutant channel from degradation and transport to the cell membrane.

VX-661 - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.921 ml9.606 ml19.212 ml
5 mM0.384 ml1.921 ml3.842 ml
10 mM0.192 ml0.961 ml1.921 ml
5 mM0.038 ml0.192 ml0.384 ml
Last Update：2024-01-02 23:10:35
VX-661
Supplier List
Shanghai Amole Biotechnology Co., Ltd.
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Product Name: (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide Request for quotation
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SKYRUN INDUSTRIAL CO.,LTD
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: VX-661 Visit Supplier Webpage Request for quotation
CAS: 1152311-62-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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Shanghai Amole Biotechnology Co., Ltd.
Featured ProductsMultiple SpecificationsSpot supply
Product Name: (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide Request for quotation
CAS: 1152311-62-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Tezacaftor (VX-661) Visit Supplier Webpage Request for quotation
CAS: 1152311-62-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: VX-661 Visit Supplier Webpage Request for quotation
CAS: 1152311-62-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: VX-661 Visit Supplier Webpage Request for quotation
CAS: 1152311-62-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
　　　　 tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: VX-661 Visit Supplier Webpage Request for quotation
CAS: 1152311-62-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: VX-661 Visit Supplier Webpage Request for quotation
CAS: 1152311-62-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
VX-661
125-12-2
2-丙烯酸
POLYURETHANEOLIGOMERS
36847-83-3
638-36-8
856629-05-5
dihydrogen wolframate
13455-36-2
35672-53-8
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