VC
L(+)-Ascorbic acid
CAS: 50-81-7
Molecular Formula: C6H8O6
VC - Names and Identifiers
| Name | L(+)-Ascorbic acid |
| Synonyms | VC Vit.C Vitamin C Vitamine C ascorbic acid Vita C BP2005 L(+)-Ascorbic Acid L(+)-Ascorbic acid L-(+)-Ascorbic acid L-Ascorbic Acid, Free Acid L-threo-hex-1-enofuranos-3-ulose 5-(1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one (non-preferred name) (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (non-preferred name) |
| CAS | 50-81-7 |
| EINECS | 200-066-2 |
| InChI | InChI=1/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2 |
VC - Physico-chemical Properties
| Molecular Formula | C6H8O6 |
| Molar Mass | 176.12 |
| Density | 1.954g/cm3 |
| Melting Point | 190-192℃ |
| Boling Point | 552.672°C at 760 mmHg |
| Specific Rotation(α) | 21 ° (C=10, H2O) |
| Flash Point | 238.199°C |
| Water Solubility | 333 g/L (20℃) |
| Solubility | Soluble in water, slightly soluble in ethanol, insoluble in ether, chloroform, benzene, petroleum ether, oil, fat. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White powder |
| Storage Condition | 2-8℃ |
| Sensitive | Sensitive to light and air |
| Refractive Index | 1.711 |
| MDL | MFCD00064328 |
| Physical and Chemical Properties | White crystals. Melting point of 190-192 ° C, soluble in water, slightly soluble in ethanol, insoluble in ether, chloroform, benzene, petroleum ether, oils and fats. Aqueous acidic reaction, in the air can be quickly oxidized to dehydroascorbic acid. Odorless, citric acid-like sour taste, is a strong reducing agent, after long storage gradient into different degrees of light yellow. |
| Use | Synthetic medicinal vitamin C is identical to natural vitamin C. The product can promote folic acid into tetrahydrofolic acid, is conducive to nucleic acid synthesis, promote the formation of red blood cells. It can also reduce ferric ions to ferrous ions, which can be easily absorbed by the human body and is also beneficial to the generation of cells. Vitamin C is involved in the production of collagen in the body. With neutralizing toxins, promote the production of antibodies, can enhance the role of the machine |
VC - Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
VC - Upstream Downstream Industry
VC - Nature
Open Data Verified Data
White Crystal or crystalline powder. Acidic. In the humid air is susceptible to oxidation and yellow. lg the product is soluble in about 3mL water, 30mL ethanol, 50mL ethanol, lOOmL glycerol, insoluble in ether, benzene, chloroform, petroleum ether, oils, fats. Flammable; Combustion produces irritating smoke.
Last Update：2025-06-10 22:55:16
VC - Preparation Method
Open Data Verified Data
with glucose as raw material, under the nickel catalyst pressure oxidation to sorbitol, and then by acetic acid bacteria fermentation oxidation to L-sorbitol, under the catalysis of concentrated sulfuric acid, it reacts with acetone to form diacetone-L-sorbitol, which is then oxidized to L-ascorbic acid by potassium permanganate under alkaline conditions.
Last Update：2025-06-10 22:55:16
VC - Uses and synthesis methods
Use as an antioxidant, can be used for fermented flour products, the maximum amount is 0.2 g/kg; it can also be used for beer, the maximum amount is 0.04 g/h. It can also be used as a food nutrition enhancer.
Use water-soluble antioxidant
Use as chemical reagent and chromatographic reagent
Use vitamin drugs, used to prevent and treat scurvy, and also used for various acute and chronic infectious diseases and purpura.
Uses Vitamin C participates in the complex metabolic process of the body, can promote growth and enhance resistance to diseases. China stipulates that it can be used to strengthen sandwich hard candy, and the usage amount is 2000~6000 mg/kg. In high-speed rail cereals and their preparation. The usage amount of products (50g of food is limited to each day) is 800~1000 mg/kg; The usage amount in fortified infant food is 300~500 mg/kg; The usage amount in fortified canned fruits is 200~400 mg/kg; The usage amount in fortified drinking liquid and milk beverage is 120~240 mg/kg; The usage amount in fortified fruit puree is 50~100 mg/kg. In addition, this product has strong reducibility and can be used as an antioxidant.
Uses Vitamin C participates in the complex metabolic process of the body, can promote growth and enhance resistance to diseases, can increase the egg production of poultry and improve the quality of eggshells. When animals lack vitamin C, they will have symptoms such as loss of appetite, growth arrest, lack of fur, and anemia. In addition, this product has strong reducibility and is a good antioxidant.
Use Synthetic medicinal vitamin C is exactly the same as natural vitamin C. The product can promote folic acid into tetrahydrofolate, which is beneficial to nucleic acid synthesis and promotes the production of red blood cells. It can also reduce ferric ions to ferric ions, which is easy to be absorbed by the human body and is also beneficial to cell formation. Vitamin C is involved in the production of collagen in the body. It can neutralize toxins and promote the production of antibodies, which can enhance the detoxification function of the body. In medicine, it is mainly used for the prevention or treatment of scurvy, as well as for dental caries, gingival abscesses, anemia, growth and development stagnation and other diseases caused by insufficient anti-blood acid.
use vitamin drugs. Participate in the process of oxidation-reduction in the body, reduce capillary fragility and increase body resistance. For vitamin C deficiency, fever, chronic wasting diseases, etc.
Use of reference reagents for the determination of arsenic, iron, phosphorus and iodine, chromatographic analysis reagents, antioxidants, masking agents, reducing agents
Production method Medicinal vitamin C is synthetic. There are many methods of synthesis. Generally, D-sorbitol is made from glucose, and then oxidized and fermented by black acetate (Acetobacter Suboxydans) to produce L-sorbose, which is condensed to form diacetone-L-sorbose, and then oxidized to produce diacetone -2-one-L-Gluconic acid, and then esterified into methyl 2-keto-L-gluconate, which reacts with sodium methoxide to form sodium ascorbate, and. If the product is given to the animal in an amount that exceeds the physiological requirement, it will be excreted from the urine. Even when taken orally in large quantities, subcutaneously or intravenously, it can be tolerated. No poisoning was found when mice were given 0.5-1.0 g/kg orally every day for 7 days or a large amount of mice were given to livestock.
Production methods Vitamin C is widely found in fresh vegetables and fruits, and chemical enzymatic methods are usually used in industrial production. Glucose is hydrogenated and reduced to D-sorbitol under the catalysis of nickel, and then oxidized and fermented with acetic acid enzyme bacteria at 30-34 ℃ and PH5.2-5.5 to generate L-sorbose. In the presence of fuming sulfuric acid and -8 ℃, L-is dissolved in acetone and condensed with it to generate diacetone sorbitose. Under the catalysis of nickel sulfate and 75-80 ℃, sodium hypochlorite is oxidized to generate di, finally, it is hydrolyzed under acidic conditions to produce 2-keto-L-gulonic acid, and then ascorbic acid is obtained.
Production methods Vitamin C is widely found in fresh vegetables and fruits, and industrial production methods usually use chemical enzymatic methods. Glucose is hydrogenated and reduced to D-sorbitol under the catalysis of nickel, and then oxidized and fermented with acetic acid mold at 30~34 ℃ and Ph value of 5.2~5.5 to produce L-sorbitose; in the presence of fuming sulfuric acid and -8 ℃, L-sorbitose is dissolved in acetone and condensed with it to form diacetone sorbitose; under the catalysis of nickel sulfate and 75~80 ℃, then sodium hypochlorite is oxidized to produce diacetone-2-keto-L-gulonic acid; finally, it is hydrolyzed under acidic conditions to produce 2-keto-L-gulonic acid, and then ascorbic acid is obtained.
production method glucose is hydrogenated and reduced to D-sorbitol under the catalysis of nickel, and then oxidized and fermented with acetic acid mold at 30~34 ℃ and Ph value of 5.2~5.5 to produce L-sorbitose. In the presence of fuming sulfuric acid and -8 ℃, L-sorbose and acetone are condensed into diacetone sorbose; in the catalysis of nickel sulfate and at 75~80 ℃, sodium hypochlorite is oxidized to generate diaceton-2-keto-L, gulonic acid; finally hydrolyzed under acidic conditions to produce 2-keto-L-gulonic acid; and then ascorbic acid is obtained.
Category toxic substances
Toxicity grading poisoning
acute toxicity oral-rat LD50: 11900 mg/kg; Oral-mouse LD50: 3367 mg/kg
Flammability hazard characteristics are flammable; combustion produces stimulating smoke
storage and transportation characteristics ventilation and low temperature drying
Fire extinguishing agent dry powder, foam, sand, carbon dioxide, mist water
Last Update：2024-04-09 20:52:54
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View History
Raw Materials for VC
Sodium methanolate
Sodium hypochlorite
2-Furoic acid
Nickel sulfate
D-Sorbitol
Sodium erythorbate
Gluconic acid
Acetonylacetone
SODIUM ERYTHORBATE
Sodium ascorbate
Acetone
Sodium hypochlorite
2-Furoic acid
Nickel sulfate
D-Sorbitol
Sodium erythorbate
Gluconic acid
Acetonylacetone
SODIUM ERYTHORBATE
Sodium ascorbate
Acetone
Downstream Products for VC
Gardenia blue pigment
Ascorbyl Palmitate
Calcium diascorbate
Sodium ascorbate
L-ASCORBYL 6-STEARATE
L-Threonic acid calcium salt
2,3-Diketo-L-gulonic acid
4-Phenylurazole
Oxalic acid
Ascorbyl Palmitate
Calcium diascorbate
Sodium ascorbate
L-ASCORBYL 6-STEARATE
L-Threonic acid calcium salt
2,3-Diketo-L-gulonic acid
4-Phenylurazole
Oxalic acid