URB754
URB754
CAS: 86672-58-4
Molecular Formula: C16H14N2O2
URB754 - Names and Identifiers
URB754 - Physico-chemical Properties
| Molecular Formula | C16H14N2O2 |
| Molar Mass | 266.29 |
| Density | 1.23±0.1 g/cm3(Predicted) |
| Melting Point | 238-240°C |
| Boling Point | 434.0±48.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Appearance | Off-white solid. |
| Color | White to Off-White |
| pKa | 3.76±0.20(Predicted) |
| Storage Condition | Refrigerator |
URB754 - Reference Information
| usage | URB754 is a potent, noncompetitive inhibitor of MGL, exhibiting an IC50 of 200 nM for the recombinant rat brain enzyme. It inhibits rat brain fatyl amide hydrolase (FAAH) less effectively with a n IC50 of 32 μ m and binds weak to the rat CB1 receptor with an IC50 of 3.8 μ m. it does not inhibit cyclooxygenase-1 (COX-1) or COX-2 at concentrations up to 100 μ m. Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management. |
Last Update：2024-04-09 20:52:54
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Product Name: URB754 Visit Supplier Webpage Request for quotation
CAS: 86672-58-4
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CAS: 86672-58-4
Tel: 18301782025
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